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Bone Marrow Mononuclear Cells CD34+ Depleted
Cat.No.: CSC-C4566X
Species: Human
Source: Bone Marrow
Cell Type: Mononuclear Cell
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CD34 depleted mononuclear cells are isolated by removing the CD34+ population from the MNCs using immunomagnetic separation. The CD34 depleted mononuclear cells contain less than 0.1% CD34+ cells. The presence of CD34+ cells is assessed by flow cytometry prior to cryopreservation.
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Description: Human bone marrow stromal cells or mesenchymal stem cells (MSCs) are derived from bone marrow mononuclear cells. MSCs are isolated from a single donor. MSCs are one of the most investigated cells for therapeutic applications. These cells enable researchers to investigate stem cell properties, regenerative medicine, and tissue engineering. In addition, they may be used for developmental studies.
Development period: Postnatal
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Development period: Postnatal
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Description: Bone Marrow is obtained from adult Myelodysplastic Syndrome patients. Bone Marrow-Mononuclear Cells are isolated by diluting the bone marrow with phosphate-buffered saline and using gradient separation techniques. After centrifugation,the Mononuclear Cells layer is collected. Mononuclear Cells can be processed further to isolate cell subpopulations. Myelodysplastic Syndrome-Mononuclear Cells are available in the newly diagnosed and relapsed/refractory stages.
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