- You are here: Home
- Services
- ISH/FISH Services
- FISH Applications
- Neoplasms FISH Analysis
Services
-
Cell Services
- Cell Line Authentication
- Cell Surface Marker Validation Service
-
Cell Line Testing and Assays
- Toxicology Assay
- Drug-Resistant Cell Models
- Cell Viability Assays
- Cell Proliferation Assays
- Cell Migration Assays
- Soft Agar Colony Formation Assay Service
- SRB Assay
- Cell Apoptosis Assays
- Cell Cycle Assays
- Cell Angiogenesis Assays
- DNA/RNA Extraction
- Custom Cell & Tissue Lysate Service
- Cellular Phosphorylation Assays
- Stability Testing
- Sterility Testing
- Endotoxin Detection and Removal
- Phagocytosis Assays
- Cell-Based Screening and Profiling Services
- 3D-Based Services
- Custom Cell Services
- Cell-based LNP Evaluation
-
Stem Cell Research
- iPSC Generation
- iPSC Characterization
-
iPSC Differentiation
- Neural Stem Cells Differentiation Service from iPSC
- Astrocyte Differentiation Service from iPSC
- Retinal Pigment Epithelium (RPE) Differentiation Service from iPSC
- Cardiomyocyte Differentiation Service from iPSC
- T Cell, NK Cell Differentiation Service from iPSC
- Hepatocyte Differentiation Service from iPSC
- Beta Cell Differentiation Service from iPSC
- Brain Organoid Differentiation Service from iPSC
- Cardiac Organoid Differentiation Service from iPSC
- Kidney Organoid Differentiation Service from iPSC
- GABAnergic Neuron Differentiation Service from iPSC
- Undifferentiated iPSC Detection
- iPSC Gene Editing
- iPSC Expanding Service
- MSC Services
- Stem Cell Assay Development and Screening
- Cell Immortalization
-
ISH/FISH Services
- In Situ Hybridization (ISH) & RNAscope Service
- Fluorescent In Situ Hybridization
- FISH Probe Design, Synthesis and Testing Service
-
FISH Applications
- Multicolor FISH (M-FISH) Analysis
- Chromosome Analysis of ES and iPS Cells
- RNA FISH in Plant Service
- Mouse Model and PDX Analysis (FISH)
- Cell Transplantation Analysis (FISH)
- In Situ Detection of CAR-T Cells & Oncolytic Viruses
- CAR-T/CAR-NK Target Assessment Service (ISH)
- ImmunoFISH Analysis (FISH+IHC)
- Splice Variant Analysis (FISH)
- Telomere Length Analysis (Q-FISH)
- Telomere Length Analysis (qPCR assay)
- FISH Analysis of Microorganisms
- Neoplasms FISH Analysis
- CARD-FISH for Environmental Microorganisms (FISH)
- FISH Quality Control Services
- QuantiGene Plex Assay
- Circulating Tumor Cell (CTC) FISH
- mtRNA Analysis (FISH)
- In Situ Detection of Chemokines/Cytokines
- In Situ Detection of Virus
- Transgene Mapping (FISH)
- Transgene Mapping (Locus Amplification & Sequencing)
- Stable Cell Line Genetic Stability Testing
- Genetic Stability Testing (Locus Amplification & Sequencing + ddPCR)
- Clonality Analysis Service (FISH)
- Karyotyping (G-banded) Service
- Animal Chromosome Analysis (G-banded) Service
- AAV Biodistribution Analysis (RNA ISH)
- Molecular Karyotyping (aCGH)
- Droplet Digital PCR (ddPCR) Service
- Digital ISH Image Quantification and Statistical Analysis
- SCE (Sister Chromatid Exchange) Analysis
- Biosample Services
- Histology Services
- Exosome Research Services
- In Vitro DMPK Services
-
In Vivo DMPK Services
- Pharmacokinetic and Toxicokinetic
- PK/PD Biomarker Analysis
- Bioavailability and Bioequivalence
- Bioanalytical Package
- Metabolite Profiling and Identification
- In Vivo Toxicity Study
- Mass Balance, Excretion and Expired Air Collection
- Administration Routes and Biofluid Sampling
- Quantitative Tissue Distribution
- Target Tissue Exposure
- In Vivo Blood-Brain-Barrier Assay
- Drug Toxicity Services
Neoplasms FISH Analysis
Creative Bioarray offers a wide menu of probes for fluorescent in situ hybridization (FISH) testing. FISH can help identify subtle or sub-microscopic structural rearrangements, variant chromosomes, and low-frequency abnormalities not readily detectable by class cytogenetics.
Panels can be customized upon request- please inquire for more details.
With many years of experience and in-depth knowledge, Creative Bioarray can use fluorescence in situ hybridization (FISH) to do the FISH analysis for you. We guarantee the speed, quality and cost of our service.
Neoplastic FISH Panel
| Panel | Probe | Target Abnormality |
| ALL panel | IGH/MYC/CEP8 | t(8;14)(q24;q32), trisomy 8 |
| CDKN2A/CEP9 | 9p21 (p16) deletion | |
| BCR/ABL1 | t(9;22)(q34;q11.2) | |
| MLL | 11q23 rearrangements | |
| TEL/AML1 | t(12;21)(p13;q22) | |
| AML panel | D7S522/D7Z1 | 7q31 deletion/ monosomy 7 |
| D8Z2 | Trisomy 8 | |
| AML1/ETO | t(8;21)(q21.3;q22) | |
| MLL | 11q23 rearrangements | |
| PML/RARA | t(15;17)(q24;q21) | |
| CBFB | t(16;16)/ inv(16)(q22) | |
| CLL panel | ATM | 11q22.3 deletion |
| D12Z3 | Trisomy 12 | |
| DLEU1/LAMP1 | 13q14 deletion/ monosomy 13 | |
| TP53 | 17p13.1 deletion | |
| IGH/CCND1 | t(11;14)(q13;q32) | |
| CML panel | BCR/ABL1 | t(9;22)(q34;q11.2) |
| 9q34 | 9q34 deletion | |
| Eosinophilia panel | PDGFRA-FIP1L1 | 4q12 deletion/rearrangement |
| PDGFRB | 5q33 rearrangements | |
| FGFR1 | 8p11.23-p11.22 rearrangements | |
| MDS panel | EGR1/D5S23 | 5q31 deletion/ monosomy 5 |
| D7S522/D7Z1 | 7q31 deletion/ monosomy 7 | |
| D8Z2 | Trisomy 8 | |
| D20S108 | 20q12 deletion | |
| MM panel | CKS1B/CDKN2C | Gain of 1q21.3 / loss of 1p32.3 |
| IGH/FGFR3 | t(4;14)(p16;q32) | |
| DLEU1/LAMP1 | 13q14 deletion/ monosomy 13 | |
| TP53 | 17p13.1 deletion | |
| 5p15 / 9q22 / 15q22 | Hyperdiploidy for chromosomes 5, 9, 15 | |
| IGH/CCND1 | t(11;14)(q13;q32) | |
| IGH Breakapart | 14q32 rearrangements | |
| IGH/MAF | t(14;16)(q32;q23) | |
| IGH/MAFB | t(14;20)(q32;q12) | |
| MPD panel | PDGFRA-FIP1L1 | 4q12 deletion/rearrangement |
| PDGFRB | 5q33 rearrangements | |
| D8Z2 | Trisomy 8 | |
| BCR/ABL1 | t(9;22)(q34;q11.2) | |
| DLEU1/LAMP1 | 13q14 deletion/ monosomy 13 | |
| D20S108 | 20q12 deletion | |
| NHL panel | BCL6 | 3q27 rearrangements |
| MYC BAP | 8q24 rearrangements | |
| IGH/CCND1 | t(11;14)(q13;q32) | |
| BIRC3/MALT1 | t(11;18)(q21;q21) | |
| IGH/BCL2 | t(14;18)(q32;q21) |
Probes that can be added to customize panel upon request
Standard Analysis:
For each FISH probe, a minimum of 200 interphase cells are analyzed for abnormal signal patterns. FISH on metaphase cells can also be performed if requested.
Features
- High accuracy and sensitively
- Fast turnaround time
- Competitive pricing
Quotations and ordering
Our customer service representatives are available 24hr a day! We thank you for choosing Creative Bioarray at your preferred Neoplasms FISH Analysis.
References
- Peterson J F, et al. Elucidating a false-negative MYC break-apart fluorescence in situ hybridization probe study by next-generation sequencing in a patient with high-grade B-cell lymphoma with IGH/MYC and IGH/BCL2 rearrangements[J]. Molecular Case Studies, 2019, 5(3): a004077.
- Zhao L, et al. Interphase fluorescence in situ hybridization analysis: A study using centromeric probes 7, 8, and 12[J]. Annals of Clinical & Laboratory Science, 1998, 28(1): 51-56.
- Haferlach, C., et al. "Mutations of the TP53 gene in acute myeloid leukemia are strongly associated with a complex aberrant karyotype." Leukemia 22.8 (2008): 1539-1541.
Explore Other Options
For research use only. Not for any other purpose.
