I-FISH Service

High-Precision Interphase Fluorescence In Situ Hybridization for Accurate Copy Number and Localization Analysis

What is I-FISH?

Interphase Fluorescence In Situ Hybridization (I-FISH) is a powerful cytogenetic technique used to detect and localize specific DNA sequences within interphase nuclei. It provides unparalleled accuracy in determining copy number variations (CNVs) and chromosomal localization of genetic elements.

Key Features of I-FISH

  • High-resolution detection of DNA sequences in interphase nuclei.
  • Precise quantification of copy number variations (CNVs).
  • Direct visualization of chromosomal integration sites.
  • Suitable for complex genetic studies and lentiviral vector analysis.

Figure 1. Determination of TNNT2 copy number in TNNT2/ACTC reporter-modified iPSCs. Representative images of I-FISH signals with complementary probe generated from TNNT2 vector in the cells at passages 34, 37, 40, 43 and 46. As a negative control, reporter unmodified cells were used. Images were taken at 100x magnification.

Applications of I-FISH

I-FISH is widely used in both research and clinical settings for a variety of applications:

Our I-FISH Service Workflow

We provide a streamlined and reliable I-FISH service to meet your research needs:

Quotation and ordering

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For research use only. Not for any other purpose.