- You are here: Home
- Disease Models
- Inflammation & Autoimmune Disease Models
- Asthma Model
- House Dust Mite (HDM)-Induced Asthma Model
Disease Models
- Oncology Models
-
Inflammation & Autoimmune Disease Models
- Rheumatoid Arthritis Models
- Glomerulonephritis Models
- Multiple Sclerosis (MS) Models
- Ocular Inflammation Models
- Sjögren's Syndrome Model
- LPS-induced Acute Lung Injury Model
- Peritonitis Models
- Passive Cutaneous Anaphylaxis Model
- Delayed-Type Hypersensitivity (DTH) Models
- Inflammatory Bowel Disease Models
- Systemic Lupus Erythematosus Animal Models
- Asthma Model
- Sepsis Model
- Psoriasis Model
- Atopic Dermatitis (AD) Model
- Scleroderma Model
- Gouty Arthritis Model
- Carrageenan-Induced Air Pouch Synovitis Model
- Carrageenan-Induced Paw Edema Model
- Experimental Autoimmune Myasthenia Gravis (EAMG) Model
- Cardiovascular Disease Models
-
Neurological Disease Models
- Alzheimer's Disease Modeling and Assays
- Seizure Models
- Parkinson's Disease Models
- Ischemic Stroke Models
- Acute Spinal Cord Injury (ASCI) Model
- Traumatic Brain Injury (TBI) Model
- Hypoxic-Ischemic Encephalopathy (HIE) Model
- Tourette Syndrome (TS) Model
- Amyotrophic Lateral Sclerosis (ALS) Model
- Huntington's Disease (HD) Model
- Intracerebral hemorrhage (ICH) Models
- Pain Models
- Metabolic Disease Models
- Liver Disease Models
- Rare Disease Models
- Respiratory Disease Models
- Digestive Disease Models
-
Urology Disease Models
- Cisplatin-induced Nephrotoxicity Model
- Unilateral Ureteral Obstruction Model
- 5/6 Nephrectomy Model
- Renal Ischemia-Reperfusion Injury (RIRI) Model
- Diabetic Nephropathy (DN) Models
- Passive Heymann Nephritis (PHN) Model
- Adenine-Induced Chronic Kidney Disease (CKD) Model
- Kidney Stone Model
- Doxorubicin-Induced Nephropathy Model
- Orthopedic Disease Models
- Ocular Disease Models
House Dust Mite (HDM)-Induced Asthma Model
Creative Bioarray provides asthma model induced by house dust mite (HDM), which has become widely used in asthma research. With our extensive experience in this field, Creative Bioarray ensures that you receive reliable and accurate results from your asthma research. Our team of experts carefully monitors and optimizes the model conditions to ensure reproducibility and consistency in the data generated. This allows you to confidently draw conclusions and make informed decisions based on your research findings.
HDM is a significant indoor allergen that plays a crucial role in the development of asthma and other allergic diseases. The HDM-induced asthma model in mice provides a valuable platform for studying the pathophysiology of these conditions and for developing new therapeutic strategies.
Our House Dust Mite (HDM)-Induced Asthma Model
- Animal Available
Mouse - Modeling Method
HDM-induced asthma model can be established by a first-step sensitization followed by consecutive intranasal administration of HDM. - Endpoints
- BALF analysis
- Serum IgE level
- H&E staining (lung)
- Lung function test (airway hyper-responsiveness)
- Cytokine analysis in lung tissue
- qPCR or Western blot
- Other customized endpoints: available upon request
Example Data
Fig. 1 H&E, PAS and Masson's trichrome staining of lung sections from different groups
Fig. 2 The counts of total inflammatory cells in BALF from mice.
Additionally, we also provide another asthma animal model that maybe you are interested in:
Quotation and Ordering
Creative Bioarray is dedicated to sharing our expertise in project design and model development. We are happy to provide the most suitable model for our clients to accelerate the development process of test compounds. If you are interested in our services, please do not hesitate to contact us at any time or submit an inquiry to us directly. We look forward to cooperating with you.
Reference
- Liu, M., et al. Progranulin protects against airway remodeling through the modulation of autophagy via HMGB1 suppression in house dust mite-induced chronic asthma. Journal of Inflammation Research, 2021: 3891-3904.
For research use only. Not for any other purpose.
