Metastasis Models

Creative Bioarray provides a diverse array of metastasis models designed to assist our clients in thoroughly assessing the efficacy of their innovative anti-cancer drug candidates. These models are meticulously crafted to mimic the complex processes of tumor spread and invasion, enabling researchers to gain deeper insights into the mechanisms of metastasis and to evaluate the potential of their therapeutic agents to inhibit this critical aspect of cancer progression.

Metastasis models serve as invaluable platforms for investigating the biological characteristics of tumors and their ability to exploit various systems within the body to facilitate metastasis. In particular, in vivo metastasis models are crucial for evaluating the anti-metastatic effects of novel anti-cancer drug candidates. While many cancer patients can undergo surgical treatment for their primary solid tumors, a significant number ultimately succumb to cancer due to refractory recurrence and metastasis. This highlights the importance of understanding the mechanisms of metastasis. Consequently, metastatic models are an essential component of the oncology toolkit, enabling researchers to explore and develop effective therapeutic strategies to combat the spread of cancer and improve patient outcomes.

Metastasis Models in Creative Bioarray

  • Available Metastasis Models
Tumor ModelTumor TypeInoculation route
MV4-11LeukemiaIV
NALM-6LeukemiaIV
JeKo-1LymphomaIV
MOLM-13LeukemiaIV
B16-F10MelanomaIV
  • Data Deliverables in Metastasis Models

Our metastasis models offer a comprehensive suite of endpoint screening services, tailored to the specific needs of each model.

Complex pancreatic tumor microenvironment featuring diverse cancer cells, active CAFs, ECM changes, abnormal blood vessels, and compromised immune response.

Example Data

Tail vein injection metastatic cancer models of Creative Bioarray.Fig. 1 Cases of Creative Bioarray's tail vein injection metastatic cancer models.

C57BL/6 mice injected with B16-F10 melanoma cells, showing lung metastases at study end.Fig. 2 Intravenous injection of B16-F10 melanoma cells into C57BL/6 mice, with lung metastases evident at the termination of the study.

Quotation and Ordering

Creative Bioarray has the expertise and capabilities to offer in vivo and in vitro preclinical oncology models. These models are designed to facilitate the successful translation of potential anti-cancer drug candidates, biologics, and devices into human clinical trials. Additionally, we can customize all of our oncology models to evaluate specific endpoints of interest.

For research use only. Not for any other purpose.