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Liver Disease Models
- Service Details
- Features
The liver is the largest internal organ in the human body, and carries out an extensive range of critical functions, such as metabolism, detoxification, protein production and storage, and immunomodulation. Liver diseases are a worldwide health threat. Liver disease is becoming more common because of lifestyle and environmental factors. Specifically, the epidemics of alcoholic liver disease, metabolic dysfunction-associated steatohepatitis (MASH, formerly NASH) and viral hepatitis have been escalating liver disease around the world.
As these chronic conditions emerged, liver fibrosis, cirrhosis and hepatocellular carcinoma also increased in prevalence. Given the prevalence of liver disease around the world and the absence of preclinical alternatives, animal models remain necessary to further unravel the pathophysiology of liver disease, find effective therapies, and to find promising biomarkers for understanding them.
Creative Bioarray is a leading liver disease modelling company with experience in alcoholic liver disease, acute liver injury, chronic liver injury, chronic fatty liver disease, ASH and non-alcoholic steatohepatitis (NASH). We strive to offer you the most sophisticated and realistic liver disease modeling to enable basic and clinical liver disease research.
Applications
- Mechanistic studies of liver diseases.
- Hepatotoxicity assessment of drugs and environmental substances.
- Evaluation of liver repair and regeneration strategies.
- Examination of liver metabolic functions.
- Preliminary screening and efficacy evaluation of new drugs.
- Exploration of therapeutic targets for liver diseases.
Our Liver Disease Models
- Alcoholic liver disease models
- Liver fibrosis model
- Acute liver injury models
- Chronic liver injury models
- Alcoholic steatohepatitis (ASH) models
- Nonalcoholic fatty liver disease (NAFLD) models
- Metabolic dysfunction-associated steatohepatitis (MASH, formerly NASH) models
We offer customizable services
- Gene editing services: Construct customized gene knockout or mutation liver disease mouse models using technologies such as CRISPR-Cas9.
- Histology and pathological analysis: Conduct advanced histological examinations on experimental animals to accurately assess disease progression and treatment efficacy.
- Pharmacodynamics research: Test the bioactivity and efficacy of new drugs in liver disease models.
- Biomarker analysis: Analyze changes in biomarkers in blood or tissues using advanced detection technologies.
- Imaging services: Employ technologies like MRI, CT, or ultrasound for non-invasive disease monitoring.
Our Advantages
- Customized service offerings: We tailor our liver disease model services and research services to perfectly align with your research needs.
- Comprehensive data analysis support: Utilize professional statistical and bioinformatics knowledge for in-depth analysis and interpretation of your experimental data.
- Efficient delivery: Provide high-quality models in the shortest possible time to support the smooth progression of your research.
Our liver disease models have been the focus of numerous groundbreaking experiments around the world, and spurred medical progress. We don't only supply the best animal models, we provide additional services such as pharmacological analysis, histopathology, and imaging for your research.
If you have any doubts about our products or services, or if you require individual support, do not hesitate to get in touch with us. Let us know how we can work with you to make some new advances in liver disease.
For research use only. Not for any other purpose.
