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Cancer Vaccine Evaluation in Humanized PBMC Mouse
For enterprises and research institutions focused on developing tumor vaccines and immunotherapies, Creative Bioarray's innovative humanized PBMC mouse model offers a cutting-edge platform that closely mimics the human immune system. This model is specifically designed for the evaluation of cancer vaccines and other immune therapies requiring antigen presentation, providing robust support for preclinical drug evaluations and significantly accelerating the R&D process. It offers a unique opportunity to investigate the human immune system's response to cancer vaccines, facilitating the development of personalized treatment strategies. Leveraging our extensive expertise, we have optimized these models for various cancer applications, ensuring their effectiveness and predictive power in the rapidly evolving field of cancer immunotherapy.
Workflow
Explore our streamlined workflow depicted in Fig. 1, designed to efficiently evaluate cancer vaccines within the humanized PBMC mouse model.
Fig. 1 Workflow of cancer vaccine evaluation in humanized PBMC mouse.
Key Advantages
- Comprehensive Immune Cell Reconstitution
Humanized PBMC mouse model in Creative Bioarray excels in reconstituting a diverse array of human-derived immune cells, including T cells, B cells, NK cells, macrophages, and dendritic cells (DCs) in murine hosts. This creates a realistic and comprehensive environment for accurate drug evaluation.
- Advantage Over Conventional Humanized PBMC Model
Unlike conventional humanized PBMC model, which typically only reconstruct T cells or NK cells, our humanized PBMC model includes the reconstitution of human myeloid cells. This expanded capacity allows for effective antigen presentation, addressing a critical limitation of traditional models.
- Enhanced Antigen Presentation Capability
Specifically designed for the evaluation of cancer vaccines and immune therapies that rely on antigen presentation, the humanized PBMC mouse model effectively simulates genuine human immune responses, making it an invaluable tool for research and development in cancer immunotherapy.
Quotation and Ordering
Ready to harness the potential of our humanized PBMC mouse model for your cancer vaccine research? Contact us today or submit an inquiry directly to learn more about how we can support your research endeavors.
For research use only. Not for any other purpose.
