- You are here: Home
- Disease Models
- Urology Disease Models
Disease Models
- Oncology Models
-
Inflammation & Autoimmune Disease Models
- Rheumatoid Arthritis Models
- Glomerulonephritis Models
- Multiple Sclerosis (MS) Models
- Ocular Inflammation Models
- Sjögren's Syndrome Model
- LPS-induced Acute Lung Injury Model
- Peritonitis Models
- Passive Cutaneous Anaphylaxis Model
- Delayed-Type Hypersensitivity (DTH) Models
- Inflammatory Bowel Disease Models
- Systemic Lupus Erythematosus Animal Models
- Asthma Model
- Sepsis Model
- Psoriasis Model
- Atopic Dermatitis (AD) Model
- Scleroderma Model
- Gouty Arthritis Model
- Carrageenan-Induced Air Pouch Synovitis Model
- Carrageenan-Induced Paw Edema Model
- Experimental Autoimmune Myasthenia Gravis (EAMG) Model
- Cardiovascular Disease Models
-
Neurological Disease Models
- Alzheimer's Disease Modeling and Assays
- Seizure Models
- Parkinson's Disease Models
- Ischemic Stroke Models
- Acute Spinal Cord Injury (ASCI) Model
- Traumatic Brain Injury (TBI) Model
- Hypoxic-Ischemic Encephalopathy (HIE) Model
- Tourette Syndrome (TS) Model
- Amyotrophic Lateral Sclerosis (ALS) Model
- Huntington's Disease (HD) Model
- Intracerebral hemorrhage (ICH) Models
- Pain Models
- Metabolic Disease Models
- Liver Disease Models
- Rare Disease Models
- Respiratory Disease Models
- Digestive Disease Models
-
Urology Disease Models
- Cisplatin-induced Nephrotoxicity Model
- Unilateral Ureteral Obstruction Model
- 5/6 Nephrectomy Model
- Renal Ischemia-Reperfusion Injury (RIRI) Model
- Diabetic Nephropathy (DN) Models
- Passive Heymann Nephritis (PHN) Model
- Adenine-Induced Chronic Kidney Disease (CKD) Model
- Kidney Stone Model
- Doxorubicin-Induced Nephropathy Model
- Orthopedic Disease Models
- Ocular Disease Models
Urology Disease Models
Urology Diseases are common clinical conditions that have irreversible long-term consequences such as kidney failure, and interfere with kidney maturation. These diseases affect people of all ages, and may result in substantial disability and impaired quality of life. Acute kidney injury and chronic kidney injury are two common types among these urology diseases.
Acute kidney injury (AKI) refers to kidney failure or kidney damage that occurs suddenly in a short period of time. AKI make it difficult for the kidneys to maintain balance of fluid in the body. It can also affect other organs, such as brain, heart, and lungs. Chronic kidney disease means lasting damage to the kidneys and getting worse over time. If the kidney eventually deteriorates to failure, the patient will need regular dialysis or a kidney transplant to survive.
At Creative Bioarray, we have successfully developed 3 urology disease models to help with drug development. The application of urology animal models helps increase our understanding of urology diseases and provides new approaches to improve the diagnosis and treatment of kidney injury.
Our portfolio of urology disease models covers
- Cisplatin-induced nephrotoxicity
- Unilateral ureteral obstruction (UUO)
- 5/6 Nephrectomy
- Renal Ischemia-Reperfusion Injury Model
- Diabetic Nephropathy Model
- Passive Heymann Nephritis Model
- Adenine-Induced Chronic Kidney Disease Model
- Kidney Stone Model
- Doxorubicin-Induced Nephropathy Model
Data & Figures
Figure 1. Histology changes of obstructed kidneys at (A) 0 day, (B) 2 days, (C) 4 days, and (D) 6 days
Quotation and ordering
We have extensive experience in developing disease models based on scientific publications. To discuss any of these models further or to discuss the possibility of developing alternative models, please do not hesitate to contact us.
Reference
Martínez-Klimova. et al. Unilateral Ureteral Obstruction as a Model to Investigate Fibrosis-Attenuating Treatments. Biomolecules. 9, (2019).
For research use only. Not for any other purpose.
