CABR™ Chromosome Probes

Creative Bioarray is dedicated to offering a portfolio of CABR^TM chromosome probes for our customers to detect the amplification, deletion, and translocation of genes and improve chromosome studies, which contain whole chromosome painting probes, centromere probes, subtelomere specific probes, satellite enumeration probes. With years of expertise, our scientists have deep FISH probes knowledge and provide customers a full range of high-quality probe products which cover every human chromosome to best match their research goals.

List of CABR^TM Chromosome Probes

Whole Chromosome Painting Probes

We have a full range of DNA probe library that uses fluorescently labeled specific chromosomes (whole chromosome, specific chromosome arm, or chromosome fragments). The DNA was prepared by chromosomal staining, and then the probe was hybridized to the mitotic phase (chromosome separation) by fluorescence in situ hybridization. When hybridization is complete, the effect of multicolor coating is produced at the hybrid site. We can then observe the fluorescent intensity on the chromosome under fluorescence microscope to analyze and study the chromosome reorganization, aberrations, and homologous genes.

Centromere Probes

Our centromere probes can bind the centromere regions of a particular chromosome to measure the number and type of specific chromosomes. The centromere probe binds to the repeating alpha satellite DNA sequence. The repetitive sequence of DNA is different from other DNA, which is tightly wound throughout the cell cycle.

Subtelomere Specific Probes

Our subtelomere specific probes have been used to focus on specific subtelomere regions and have evolved in new disease syndrome studies. Subtelomeres specific probes can also be used for autism, recurrent miscarriage and other aspects of research.

Satellite Enumeration Probes

We provide CABR^TM satellite enumeration probes specifically recognize highly repetitive DNA sequences in 24 human chromosomes. These highly repetitive DNA sequences are present in the chromosomal centromere, centromere, and heterochromatin regions.

Our Advantages

• Our chromosome probes products are highly specific and sensitive in the identification of human pathology.
• Our centromere probes can be used for the detection of chromosome monomeric or aneuploidy, and also can be a reference probe for other genes.
• Our subtelomere specific probes are selected from the unique sequence at the end to obtain the most probable chromosome specificity that can be used for routine subtelomeres enumeration and integrity testing.

Creative Bioarray has spent years of hardworking in the chromosome probe field. We are very glad to provide our clients with high-quality chromosome probes to meet your needs. Not only our products are efficient and available at low cost, but also our experts will try their best to offer the professional assistance for you. If you have any additional requirements or questions, please do not hesitate to contact us. We look forward to working with you in the future.

How to Choose the Right Chromosome Probe?

Selecting the appropriate chromosome probe is critical for achieving accurate and reliable results in your research or diagnostic applications. Here are some key factors to consider when choosing the right probe:

1. Application Purpose:
   • Determine the specific application of the probe, such as detecting chromosomal abnormalities, identifying structural rearrangements, or performing gene mapping.
   • For example, if you are studying trisomy 21 (Down syndrome), a probe targeting chromosome 21 would be ideal.
2. Probe Type:
   • Centromeric Probes: Ideal for detecting aneuploidy or numerical abnormalities.
   • Locus-Specific Probes: Best for identifying specific gene regions or structural changes.
   • Whole Chromosome Paint Probes: Useful for visualizing entire chromosomes and detecting translocations.
3. Sample Type:
   • Consider the type of sample you are working with (e.g., blood, tissue, cultured cells) and ensure the probe is compatible with your sample preparation method.
4. Sensitivity and Specificity:
   • Choose probes with high sensitivity and specificity to ensure accurate hybridization and minimize background noise.
5. Customization Needs:
   • If your research requires unique or rare targets, consider custom probe design services to meet your specific requirements.
6. Technical Support:
   • Creative Bioarray provides comprehensive technical support and troubleshooting assistance to ensure smooth implementation in your workflow.

At Creative Bioarray, we offer a wide range of chromosome probes tailored to meet diverse research and diagnostic needs. Our team of experts is available to guide you in selecting the most suitable probe for your project.

How Do Our Chromosome Probes Improve Experimental Efficiency?

Our chromosome probes are designed to streamline your workflow and deliver reliable results, saving you time and resources. Here's how they can enhance your experimental efficiency:

1. High-Quality Manufacturing:
   • Our probes are manufactured under strict quality control standards to ensure consistent performance, reducing the need for repeat experiments.
2. Optimized Hybridization Protocols:
   • Each probe comes with a detailed protocol optimized for fast and efficient hybridization, minimizing hands-on time and maximizing productivity.
3. Customizable Solutions:
   • We offer custom probe design services to meet your unique research needs, eliminating the time-consuming process of designing and validating probes yourself.
4. Comprehensive Product Range:
   • With a wide selection of ready-to-use probes, you can quickly find the right product for your application without delays.
5. Technical Support and Troubleshooting:
   • Our dedicated technical support team is available to assist you at every step, from probe selection to experimental setup, ensuring smooth and efficient workflows.
6. Reliable Results:
   • Our probes are designed for high sensitivity and specificity, reducing background noise and ensuring clear, interpretable results in less time.

By choosing Creative Bioarray's chromosome probes, you can focus on your research goals while we provide the tools and support to make your experiments more efficient and successful.