Animal Chromosome Analysis (G-banded) Service
- Service Details
- Features
- Applications
- FAQ
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G-banding analysis represents a foundational technology in cytogenetic research. Trypsin treatment followed by Giemsa staining produces a visible chromosome banding pattern under a microscope which enables detection of numerical chromosome anomalies such as aneuploidy and polyploidy together with structural changes like translocation, inversion, and deletion. These abnormalities correlate strongly with reproductive disorders and developmental malformations in animals while also leading to hereditary diseases and population degradation.
Our service is dedicated to providing high-quality chromosome analysis for research institutions, breeding companies, and biotechnology enterprises. Our team possesses deep chromosome analysis experience with multiple species such as humans, mice, rats, pigs, sheep, cows, chickens, hamsters, dogs, elephants, dolphins, salmon and insects and has developed adult and embryonic stem cell lines. Additionally, our customized chromosome analysis services are developed to meet your exact requirements so you can build sound research and development projects on a dependable foundation.
Fig. 1. Karyotype generated from chicken, bovine, cat and pig cells.
Creative Bioarray's Animal Chromosome Analysis (G-banded) Service
Workflow
1
Sample Collection
We support a variety of sample types, including peripheral blood, bone marrow, tissues, and embryonic stem cells. Professional guidance for sample collection is available.
2
Cell Culture
For live cell samples, we conduct proper culturing to obtain an adequate number of metaphase cells.
3
Chromosome Harvesting
Meticulously timed to ensure peak mitotic activity, harvesting prepares chromosomes for subsequent analysis.
4
G-banding Preparation
Chromosomes are stained to reveal characteristic band patterns.
5
Microscopic Imaging and Analysis
We examine 30-40 metaphase cells, analyze chromosome number and structural abnormalities, and produce standardized karyotype images.
Species
- Humans (adult and embryonic stem cell lines)
- Laboratory animals (such as mice, rats, hamsters)
- Livestock and pets (such as cows, pigs, sheep, horses, dogs, cats)
- Wildlife animals (such as elephants, dolphins, salmon)
- Insects
Detections
- Chromosomal number abnormalities (such as aneuploidy, polyploidy)
- Chromosomal structural abnormalities (such as deletions, duplications, inversions, translocations)
- Sex chromosome analysis
- Karyotype analysis for specific species
Deliverables
- A high-resolution set of chromosome G-banded images.
- A detailed karyotype analysis report, including chromosome numbers, morphology, banding characteristics, and potential variance information.
Features
Multi-Species Experience
We support chromosome analysis in a wide variety of animal species, including those with complex karyotypes and rare species.
Customized Services
Offering personalized chromosome analysis plans tailored to customers’ specific needs.
Rapid Turnaround
Standard service reports are delivered within 7-10 business days, with expedited service available for quicker delivery.
Comprehensive Support
Our support team guides you through each phase of the process from sample collection until final report interpretation.
What can You do with Our Animal Chromosome Analysis (G-banded) Service?
Our services support a wide range of applications:
- Animal Breeding and Reproduction: Screen for chromosome translocation carriers to reduce genetic defect transmission and enhance reproductive efficiency.
- Disease Model Development: Assess gene-edited animal models (such as those modified by CRISPR) for chromosomal stability to maintain experimental dependability.
- Endangered Species Conservation: Examine wildlife chromosomal diversity to inform the development of effective conservation strategies.
- Reproductive Health Research: Identify chromosomal defects that lead to animal infertility to enhance reproductive treatment approaches.
- Cell Line Quality Control: Evaluate genetic stability in stem cells or tumor cell lines, preventing experimental deviation.
FAQ
1. What types of samples are required?
We accept various types of samples, such as blood, bone marrow, and skin tissues. Please ensure samples are fresh and sterile. Refer to our sample collection guide or contact our technical support team for specific collection methods.
2. Which animal species' chromosome analysis do you support?
Our service supports chromosome analysis for many animal species which include humans, mice, rats, pigs, sheep, cows, chickens, hamsters, dogs, elephants, dolphins, salmon among others in addition to various insects. Please contact us to confirm requirements for specific species.
3. What types of chromosomal abnormalities can G-banding analysis detect?
G-banding technology identifies both numerical chromosome abnormalities including aneuploidy and polyploidy as well as structural chromosome alterations like deletions and translocations. Further analysis of subtle variations requires combining G-banding with additional techniques such as FISH or sequencing.
4. What is the service timeline?
Typically, the service timeline is 7-10 business days from receiving qualified samples. However, the timeline may extend due to sample quality issues or specific experimental requirements. We will communicate promptly with customers.
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