Life Science Articles
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Cell - Related Articles
2022 |
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Porpiglia E, Mai T, Kraft P, Holbrook CA, de Morree A, Gonzalez VD, Hilgendorf KI, Frésard L, Trejo A, Bhimaraju S, Jackson PK, Fantl WJ, Blau HM. (2022). Elevated CD47 is a hallmark of dysfunctional aged muscle stem cells that can be targeted to augment regeneration. Cell Stem Cell. 29 (12), 1653-1668. |
Analysis of Molecular Classification and Biomarkers in Breast Ductal Carcinoma in Situ Strand SH, et al. (2022). Molecular classification and biomarkers of clinical outcome in breast ductal carcinoma in situ: Analysis of TBCRC 038 and RAHBT cohorts. Cancer Cell. S1535-6108 (22), 00512-8. |
Myeloid Cells Promote Deterioration of the Hematopoietic System Feyen J, Ping Z, Chen L, van Dijk C, van Tienhoven TVD, van Strien PMH, Hoogenboezem RM, Wevers MJW, Sanders MA, Touw IP, Raaijmakers MHGP. (2022). Myeloid cells promote interferon signaling-associated deterioration of the hematopoietic system. Nature Communications. 13 (1), 7657. |
Ennerfelt H, Frost EL, Shapiro DA, Holliday C, Zengeler KE, Voithofer G, Bolte AC, Lammert CR, Kulas JA, Ulland TK, Lukens JR. (2022). SYK coordinates neuroprotective microglial responses in neurodegenerative disease. Cell. 185 (22), 4135-4152. |
Pantazis CB, et al. (2022). A reference human induced pluripotent stem cell line for large-scale collaborative studies. Cell Stem Cell. 29(12), 1685-1702. |
2023 |
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Gao Y, Cheng Y, Wen J, Xiao D, Xu J, Cai C, Hu J. (2023). Efficient generation of induced pluripotent stem cell lines from peripheral blood mononuclear cells. Stem Cell Research. 69: 103088. |
Iqbal W, Wang Y, Sun P, Zhou X. (2023). Modeling Liver Development and Disease in a Dish. International Journal of Molecular Sciences. 24 (21): 15921. |
Ávila-González D, Gidi-Grenat MÁ, García-López G, Martínez-Juárez A, Molina-Hernández A, Portillo W, Díaz-Martínez NE, Díaz NF. (2023). Pluripotent Stem Cells as a Model for Human Embryogenesis. Cells. 12 (8), 1192. |
Maalej KM, Merhi M, Inchakalody VP, Mestiri S, Alam M, Maccalli C, Cherif H, Uddin S, Steinhoff M, Marincola FM, Dermime S. (2023). CAR-cell therapy in the era of solid tumor treatment: current challenges and emerging therapeutic advances. Molecular Cancer. 22 (1), 20. |
Zhang L, Chen W, Liu S, Chen C. (2023). Targeting Breast Cancer Stem Cells. International Journal of Biological Sciences. 19 (2), 552-570. |
Karnas E, Dudek P, Zuba-Surma EK. (2023). Stem cell-derived extracellular vesicles as new tools in regenerative medicine - Immunomodulatory role and future perspectives. Frontiers in Immunology. 14, 11201759. |
In Vitro Cellular Reprogramming to Model Disorders of Sex Development Gonen N, Eozenou C, Mitter R, Elzaiat M, Stévant I, Aviram R, Bernardo AS, Chervova A, Wankanit S, Frachon E, Commère PH, Brailly-Tabard S, Valon L, Barrio Cano L, Levayer R, Mazen I, Gobaa S, Smith JC, McElreavey K, Lovell-Badge R, Bashamboo A. (2023). In vitro cellular reprogramming to model gonad development and its disorders. Science Advances. 9(1), eabn9793. |
Senescent Cells Perturb Intestinal Stem Cell Differentiation Through Ptk7 Yun J, Hansen S, Morris O, Madden DT, Libeu CP, Kumar AJ, Wehrfritz C, Nile AH, Zhang Y, Zhou L, Liang Y, Modrusan Z, Chen MB, Overall CC, Garfield D, Campisi J, Schilling B, Hannoush RN, Jasper H. (2023). Senescent cells perturb intestinal stem cell differentiation through Ptk7 induced noncanonical Wnt and YAP signaling. Nature Communications. 14(1), 156. |
Wells MF, Nemesh J, Ghosh S, Mitchell JM, Salick MR, Mello CJ, Meyer D, Pietilainen O, Piccioni F, Guss EJ, Raghunathan K, Tegtmeyer M, Hawes D, Neumann A, Worringer KA, Ho D, Kommineni S, Chan K, Peterson BK, Raymond JJ, Gold JT, Siekmann MT, Zuccaro E, Nehme R, Kaykas A, Eggan K, McCarroll SA. (2023). Natural variation in gene expression and viral susceptibility revealed by neural progenitor cell villages. Cell Stem Cell. S1934-5909(23)00035-8. |
Inactive Disease in Lupus Patients Normalizes Ifnα and B-Cell Subsets Bradford HF, Haljasmägi L, Menon M, McDonnell TCR, Särekannu K, Vanker M, Peterson P, Wincup C, Abida R, Gonzalez RF, Bondet V, Duffy D, Isenberg DA, Kisand K, Mauri C. (2023). Inactive disease in patients with lupus is linked to autoantibodies to type I interferons that normalize blood IFNα and B cell subsets. Cell Reports Medicine. 4 (1), 100894. |
Gerace D, Zhou Q, Kenty JH, Veres A, Sintov E, Wang X, Boulanger KR, Li H, Melton DA. (2023). Engineering human stem cell-derived islets to evade immune rejection and promote localized immune tolerance. Cell Reports Medicine. 4 (1), 100879. |
Multiscale 3D Genome Reorganization of Skeletal Muscle Stem Cells Zhao Y, Ding Y, He L, Zhou Q, Chen X, Li Y, Alfonsi MV, Wu Z, Sun H, Wang H. (2023). Multiscale 3D genome reorganization during skeletal muscle stem cell lineage progression and aging. Science Advances. 9 (7): eabo1360. |
Jimenez-Tellez N, Vera CD, Yildirim Z, Vicente Guevara J, Zhang T, Wu JC. (2023). Generation of two iPSC lines from long QT syndrome patients carrying SNTA1 variants. Stem Cell Research. 66: 103003. |
Generation of NRF2 Knockout iPSC Clones Using CRISPR/Cas9 Editing Merkert S, Haase A, Dahlmann J, Göhring G, Waqas FH, Pessler F, Martin U, Olmer R. (2023). Generation of two human NRF2 knockout iPSC clones using CRISPR/Cas9 editing. Stem Cell Research. 69: 103090. |
Characterization of Transplantation of Human iPSC Neuronal Precursors Kobayashi Y, Shigyo M, Platoshyn O, Marsala S, Kato T Jr, Takamura N, Yoshida K, Kishino A, Bravo-Hernandez M, Juhas S, Juhasova J, Studenovska H, Proks V, Driscoll SP, Glenn TD, Pfaff SL, Ciacci JD, Marsala M. (2023). Expandable Sendai-Virus-Reprogrammed Human iPSC-Neuronal Precursors: In Vivo Post-Grafting Safety Characterization in Rats and Adult Pig. Cell Transplantation. 32: 9636897221107009. |
Suresh Babu S, Duvvuru H, Baker J, Switalski S, Shafa M, Panchalingam KM, Dadgar S, Beller J, Ahmadian Baghbaderani B. (2023). Characterization of human induced pluripotent stem cells: Current approaches, challenges, and future solutions. Biotechnology Reports. 37: e00784. |
Ito R, Kimura A, Hirose Y, Hatano Y, Mima A, Mae SI, Keidai Y, Nakamura T, Fujikura J, Nishi Y, Ohta A, Toyoda T, Inagaki N, Osafune K. (2023). Elucidation of HHEX in pancreatic endoderm differentiation using a human iPSC differentiation model. Scientific Reports. 13 (1): 8659. |
2024 |
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Gleixner S, Zahn I, Dietrich J, Singh S, Drobny A, Schneider Y, Schwendner R, Socher E, Blavet N, Bräuer L, Gostian AO, Balk M, Schulze-Tanzil G, Günther C, Paulsen F, Arnold P. (2024). A New Immortalized Human Lacrimal Gland Cell Line. Cells. 13 (7): 622. |
Immortalization of Horse-Derived Fibroblast by Cell Cycle Regulator Tani T. (2024). Immortalization of American miniature horse-derived fibroblast by cell cycle regulator with normal karyotype. PeerJ Life & Environment. 12: e16832. |
Establishment of Cell Lines Using a Non-viral Immortalization Approach Lange S, Kuntze A, Wüstmann N, Reckers T, Humberg V, Dirks WG, Huss S, Vieler J, Schrader AJ, Bögemann M, Schlack K, Bernemann C. (2024). Establishment of primary prostate epithelial and tumorigenic cell lines using a non-viral immortalization approach. Biological Research. 57 (1): 21. |
Chalak M, Hesaraki M, Mirbahari SN, Yeganeh M, Abdi S, Rajabi S, Hemmatzadeh F. (2024). Cell Immortality: In Vitro Effective Techniques to Achieve and Investigate Its Applications and Challenges. Life (Basel). 14 (3): 417. |
Guo Q, Qian ZM. (2024). Macrophage-based drug delivery: Key challenges and strategies. Bioactive Materials. 38: 55-72. |
Calothrixin B Derivatives Induce Apoptosis and Cell Cycle Arrest in HEL Cells Wang B, Wang M, Li K, Wang C, Liu X, Rao Q, Song J, Hang Y, Liu S, Wen M, Huang L, Li Y. (2024). Calothrixin B derivatives induce apoptosis and cell cycle arrest on HEL cells through the ERK/Ras/Raf/MEK pathway. Biomedicine and Pharmacotherapy. 171: 116179. |
Tan F, Li X, Wang Z, Li J, Shahzad K, Zheng J. (2024). Clinical applications of stem cell-derived exosomes. Signal Transduction and Targeted Therapy. 9 (1): 17. |
Maličev E, Jazbec K. (2024). An Overview of Mesenchymal Stem Cell Heterogeneity and Concentration. Pharmaceuticals (Basel). 17 (3): 350. |
Impacts of NK Cell-Surface Receptors on CAR-NK Efficacy in Solid Tumors Wang W, Liu Y, He Z, Li L, Liu S, Jiang M, Zhao B, Deng M, Wang W, Mi X, Sun Z, Ge X. (2024). Breakthrough of solid tumor treatment: CAR-NK immunotherapy. Cell Death Discovery. 10 (1): 40. |
Şen B, Balcı-Peynircioğlu B. (2024). Cellular models in autoinflammatory disease research. Clinical and Translational Immunology. 13 (1): e1481. |
A Report of Regase-2 Inhibiting Glioblastoma Cell Proliferation Sowinska W, Wawro M, Kochan J, Solecka A, Polak J, Kwinta B, Kasza A. (2024). Regnase-2 inhibits glioblastoma cell proliferation. Scientific Reports. 14 (1): 1574. |
Bai M, Jiang N, Fu W, Huang C, Tian L, Mi N, Gao L, Ma H, Lu Y, Cao J, Zhang C, Yue P, Zhang Y, Lin Y, Meng W, Li X. (2024). Establishment and characterization of a novel hilar cholangiocarcinoma cell line, CBC3T-1. Human Cell. 37(1): 364-375 |
Histology – Related Articles
2022 |
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Comparative Research of IHC and FISH in HER 2 / Neu Gene Detection Aznab M, Izadi B, Amirian F, Khazaei S, Madani SH, Ramezani M. (2022). Comparison of Immunohistochemical Methods (IHC) and Fluorescent in Situ Hybridization (FISH) in the Detection of HER 2 /Neu Gene in Kurdish Patients with Breast Cancer in Western Iran. International Journal of Hematology-Oncology Stem Cell Research. 16 (4), 217-223. |
Analysis of Molecular Classification and Biomarkers in Breast Ductal Carcinoma in Situ Strand SH, et al. (2022). Molecular classification and biomarkers of clinical outcome in breast ductal carcinoma in situ: Analysis of TBCRC 038 and RAHBT cohorts. Cancer Cell. S1535-6108 (22), 00512-8. |
2023 |
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A Novel Method for Detection of IGH::CRLF2 Gene Fusions by FISH González-Arreola RM, García-Romero A, Magaña-Torres MT, González-García JR. (2023). A novel approach for direct detection of the IGH::CRLF2 gene fusion by fluorescent in situ hybridization. Molecular Cytogenetics. 16 (1): 19. |
Gianesini S, Rimondi E, Raffetto JD, Melloni E, Pellati A, Menegatti E, Avruscio GP, Bassetto F, Costa AL, Rockson S. (2023). Human collecting lymphatic glycocalyx identification by electron microscopy and immunohistochemistry. Scientific Reports. 13 (1), 3022. |
van Gulik AL, Sluydts E, Vervoort L, Kockx M, Kortman P, Ylstra B, Finn SP, Bubendorf L, Bahce I, Sie D, Radonic T, Lissenberg-Witte B, Thunnissen E. (2023). False positivity in break apart fluorescence in-situ hybridization due to polyploidy. Translation Lung Cancer Research. 12 (4), 676-688. |
Microscopy Studies of Synapses in Alzheimer's Disease Tissue Griffiths J and Grant SGN. (2023). Synapse pathology in Alzheimer's disease. Seminars in Cell & Development Biology. 139, 13-23. |
Senescent Cells Perturb Intestinal Stem Cell Differentiation Through Ptk7 Yun J, Hansen S, Morris O, Madden DT, Libeu CP, Kumar AJ, Wehrfritz C, Nile AH, Zhang Y, Zhou L, Liang Y, Modrusan Z, Chen MB, Overall CC, Garfield D, Campisi J, Schilling B, Hannoush RN, Jasper H. (2023). Senescent cells perturb intestinal stem cell differentiation through Ptk7 induced noncanonical Wnt and YAP signaling. Nature Communications. 14(1), 156. |
Dual-Modality Imaging of IF and IMC Kim EN, Chen PZ, Bressan D, Tripathi M, Miremadi A, di Pietro M, Coussens LM, Hannon GJ, Fitzgerald RC, Zhuang L, Chang YH. (2023). Dual-modality imaging of immunofluorescence and imaging mass cytometry for whole slide imaging with accurate single-cell segmentation. BioRxiv [Preprint]. 2023.02.23: 529718. |
Deep Immunohistochemistry for 3D Histology Yau CN, Lai HM, Lee K, Kwok AJ, Huang J, Ko H. (2023). Principles of deep immunohistochemistry for 3D histology. Cell Reports Methods. 3 (5): 100458. |
Visualization of Inflammatory Gene Products in Neuronal Cells by RNAscope and IHC Ball JB, McNulty CJ, Green-Fulgham SM, Dragavon JM, Correia Rocha IR, Finch MR, Prévost ED, Siddique II, Woodall BJ, Watkins LR, Baratta MV, Root DH. (2023). Combining RNAscope and immunohistochemistry to visualize inflammatory gene products in neurons and microglia. Frontier in Molecular Neuroscience. 16: 1225847. |
Barbosa A, Miranda S, Azevedo NF, Cerqueira L, Azevedo AS. (2023). Imaging biofilms using fluorescence in situ hybridization: seeing is believing. Frontiers in Cellular Infection Microbiology. 13: 1195803 |
2024 |
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Kalhor K, Chen CJ, Lee HS, Cai M, Nafisi M, Que R, Palmer CR, Yuan Y, Zhang Y, Li X, Song J, Knoten A, Lake BB, Gaut JP, Keene CD, Lein E, Kharchenko PV, Chun J, Jain S, Fan JB, Zhang K. (2024). Mapping human tissues with highly multiplexed RNA in situ hybridization. Nature Communications. 15 (1): 2511. |
Zhang X, Li L, Gao F, Liu B, Li J, Ren S, Peng S, Qiu W, Pu X, Ye Q. (2024). Fluorescent in situ hybridization has limitations in screening NRG1 gene rearrangements. Diagnostic Pathology. 19 (1): 1. |
Validation of Dual-Color Dual ISH for HER2/neu Gene in Breast Cancer Rathi A, Sahay A, Shet TM, Patil A, Desai SB. (2024). Validation of Dual-Color Dual In Situ Hybridization for HER2/neu Gene in Breast Cancer. Archives of Pathology & Laboratory Medicine. 148 (4): 453-460. |
Febres-Aldana CA, Chang JC, Jungbluth AA, Adusumilli PS, Bodd FM, Frosina D, Geronimo JA, Hernandez E, Irawan H, Offin MD, Rekhtman N, Travis WD, Vanderbilt C, Zauderer MG, Zhang Y, Ladanyi M, Yang SR, Sauter JL. (2024). Comparison of Immunohistochemistry, Next-generation Sequencing and Fluorescence In Situ Hybridization for Detection of MTAP Loss in Pleural Mesothelioma. Modern Pathology. 37 (3): 100420. |
Evolutionary Biology of Minor Gain/amp(1q) Clone Revealed by FISH Cui J, Liu Y, Lv R, Yan W, Xu J, Li L, Du C, Yu T, Zhang S, Deng S, Sui W, Hao M, Yi S, Zou D, Qiu L, Xu Y, An G. (2024). Fluorescence in situ hybridization reveals the evolutionary biology of the minor clone of gain/amp(1q) in multiple myeloma. Leukemia. 38 (6): 1299-1306. |
B-Cell Tumors With t(14;19)(q32;q13)/IGH::BCL3 Identified by G-Banding and FISH Ohno H, Maekawa F, Hayashida M, Nakagawa M, Fukutsuka K, Matsumura M, Takeoka K, Maruyama W, Ukyo N, Sumiyoshi S, Tanaka Y, Haga H. (2024). Diverse B-cell tumors associated with t(14;19)(q32;q13)/IGH::BCL3 identified by G-banding and fluorescence in situ hybridization. Journal of Clinical and Experimental Hematopathology. 64 (1): 21-31. |
Laboratory Techniques to Detect Chromosomal Abnormalities in Multiple Myeloma Clarke SE, Fuller KA, Erber WN. (2024). Chromosomal defects in multiple myeloma. Blood Reviews. 64: 101168. |
Exosome - Related Articles
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Exosome-Mediated Delivery of Cas9 Ribonucleoprotein Complexes Wan T, Zhong J, Pan Q, Zhou T, Ping Y, Liu X. (2022). Exosome-mediated delivery of Cas9 ribonucleoprotein complexes for tissue-specific gene therapy of liver diseases. Science Advance. 8 (37), eabp9435. |
An Exosome-Related RNA Risk Model for Predicting Breast Cancer Qiu P, Guo Q, Lin J, Pan K, Chen J, Ding M. (2022). An exosome-related long non-coding RNAs risk model could predict survival outcomes in patients with breast cancer. Scientific Reports. 12(1), 22322. |
Rezaie J, Feghhi M, Etemadi T. (2022). A review on exosomes application in clinical trials: perspective, questions, and challenges. Cell Communication and Signaling. 20 (1), 145. |
2023 |
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Peng Y, Yang Y, Li Y, Shi T, Luan Y, Yin C. (2023). Exosome and virus infection. Frontiers in Immunology. 14: 1154217. |
Steć A, Targońska M, Karkosińska E, Słowik M, Płoska A, Kalinowski L, Wielgomas B, Waleron K, Jasiecki J, Dziomba S. (2023). Protein overproduction alters exosome secretion in Chinese hamster ovary cells. Analytical and Bioanalytical Chemistry. 415 (16): 3167-3176. |
Lau NCH and Yam JWP. (2023). From Exosome Biogenesis to Absorption: Key Takeaways for Cancer Research. Cancers (Basel). 15 (7), 1992. |
An Exosome-Related RNA Risk Model for Predicting Breast Cancer Qiu P, Guo Q, Lin J, Pan K, Chen J, Ding M. (2022). An exosome-related long non-coding RNAs risk model could predict survival outcomes in patients with breast cancer. Scientific Reports. 12(1), 22322. |
Kar R, Dhar R, Mukherjee S, Nag S, Gorai S, Mukerjee N, Mukherjee D, Vatsa R, Chandrakanth Jadhav M, Ghosh A, Devi A, Krishnan A, Thorat ND. (2023). Exosome-Based Smart Drug Delivery Tool for Cancer Theranostics. ACS Biomaterials Science Engineering. 9 (2): 577-594. |
Isolation and Characterization of Exosomes from Non-Small Lung Cancer Cells Mahgoub EO, Abdella GM. (2023). Improved exosome isolation methods from non-small lung cancer cells (NC1975) and their characterization using morphological and surface protein biomarker methods. Journal of Cancer Research and Clinical Oncology. 149 (10): 7505-7514. |
Applications Exosomes in Inflammatory Diseases Yang Y, Peng Y, Li Y, Shi T, Luan Y, Yin C. (2023). Role of stem cell derivatives in inflammatory diseases. Frontiers in Immunology. 14: 1153901. |
2024 |
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Tan F, Li X, Wang Z, Li J, Shahzad K, Zheng J. (2024). Clinical applications of stem cell-derived exosomes. Signal Transduction and Targeted Therapy. 9 (1): 17. |
Huber CC, Wang H. (2024). Pathogenic and therapeutic role of exosomes in neurodegenerative disorders. Neural Regeneration Research. 19 (1): 75-79. |
What Is the Role of Macrophage-Derived Exosomes in Gastric Cancer Progression? Qiu Y, Lu G, Li N, Hu Y, Tan H, Jiang C. (2024). Exosome-mediated communication between gastric cancer cells and macrophages: implications for tumor microenvironment. Frontiers in Immunology. 15: 1327281. |
Dai Z, Cai R, Zeng H, Zhu H, Dou Y, Sun S. (2024). Exosomes may be the next generation of promising cell-free vaccines. Human Vaccines & Immunotherapeutics. 20 (1): 2345940. |
Exosome MicroRNA-22 Inhibiting Proliferation, Migration, and Invasion in OS Ruan Q, Wang C, Wu Y, Zhu Q. (2024). Exosome microRNA-22 inhibiting proliferation, migration, and invasion through regulating Twist1/CADM1 axis in osteosarcoma. Scientific Reports. 14 (1): 761. |
Exosomal Delivery of miR‐410‐3p Reverses Trophoblast EMT, Migration and Invasion Chen ZY, Li Z, Zong Y, Xia B, Luo SP, Deng GP, Gao J. (2024). Exosome-delivered miR-410-3p reverses epithelial-mesenchymal transition, migration, and invasion of trophoblasts in spontaneous abortion. Journal of Cellular and Molecular Medicine. 28 (3): e18097. |
Cancer - Related Articles
2022 |
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Comparative Research of IHC and FISH in HER 2 / Neu Gene Detection Aznab M, Izadi B, Amirian F, Khazaei S, Madani SH, Ramezani M. (2022). Comparison of Immunohistochemical Methods (IHC) and Fluorescent in Situ Hybridization (FISH) in the Detection of HER 2 /Neu Gene in Kurdish Patients with Breast Cancer in Western Iran. International Journal of Hematology-Oncology Stem Cell Research. 16 (4), 217-223. |
Ranasinghe R, Mathai ML, Zulli A. (2022). Cisplatin for cancer therapy and overcoming chemoresistance. Heliyon. 8 (9): e10608. |
2023 |
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van Gulik AL, Sluydts E, Vervoort L, Kockx M, Kortman P, Ylstra B, Finn SP, Bubendorf L, Bahce I, Sie D, Radonic T, Lissenberg-Witte B, Thunnissen E. (2023). False positivity in break apart fluorescence in-situ hybridization due to polyploidy. Translation Lung Cancer Research. 12 (4), 676-688. |
Lau NCH and Yam JWP. (2023). From Exosome Biogenesis to Absorption: Key Takeaways for Cancer Research. Cancers (Basel). 15 (7), 1992. |
Gong Z, Li Q, Shi J, Li P, Hua L, Shultz LD, Ren G. (2023). Immunosuppressive reprogramming of neutrophils by lung mesenchymal cells promotes breast cancer metastasis. Science Immunology. 8 (80): eadd5204. |
Nicodemou A, Bernátová S, Čeháková M, Danišovič Ľ. (2023). Emerging Roles of Mesenchymal Stem/Stromal-Cell-Derived Extracellular Vesicles in Cancer Therapy. Pharmaceutics. 15 (5), 1453. |
Xu H, Chai CP, Miao X, Tang H, Hu JJ, Zhang H, Zhou WC. (2023). Establishment and characterization of a new human ampullary carcinoma cell line, DPC-X1. World Journal of Gastroenterology. 29 (17), 2642-2656. |
Oreff GL, Maurer B, ELKhamary AN, Gerner I, Sexl V, Jenner F. (2023). Immortalized murine tenocyte cells: a novel and innovative tool for tendon research. Scientific Reports. 13 (1), 1566. |
Studies on Prostate Tumor Cells Triggered by Photodynamic Therapy de Melo Gomes LC, de Oliveira Cunha AB, Peixoto LFF, Zanon RG, Botelho FV, Silva MJB, Pinto-Fochi ME, Góes RM, de Paoli F, Ribeiro DL. (2023). Photodynamic therapy reduces cell viability, migration and triggers necroptosis in prostate tumor cells. Photochemical & Photobiological Sciences. 22 (6), 1341-1356. |
Isolation and Characterization of Exosomes from Non-Small Lung Cancer Cells Mahgoub EO, Abdella GM. (2023). Improved exosome isolation methods from non-small lung cancer cells (NC1975) and their characterization using morphological and surface protein biomarker methods. Journal of Cancer Research and Clinical Oncology. 149 (10): 7505-7514. |
Yuan J, Li X, Yu S. (2023). Cancer organoid co-culture model system: Novel approach to guide precision medicine. Frontiers in Immunology. 13: 1061388. |
Biological Features of Circulating Tumor Cells Ring A, Nguyen-Sträuli BD, Wicki A, Aceto N. (2023). Biology, vulnerabilities and clinical applications of circulating tumor cells. Nature Reviews Cancer. 23 (2): 95-111. |
Ovarian Cancer Stem Cell-Related Signaling Pathways Ma H, Tian T, Cui Z. (2023). Targeting ovarian cancer stem cells: a new way out. Stem Cell Research and Therapy. 14 (1): 28. |
2024 |
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Impacts of NK Cell-Surface Receptors on CAR-NK Efficacy in Solid Tumors Wang W, Liu Y, He Z, Li L, Liu S, Jiang M, Zhao B, Deng M, Wang W, Mi X, Sun Z, Ge X. (2024). Breakthrough of solid tumor treatment: CAR-NK immunotherapy. Cell Death Discovery. 10 (1): 40. |
Bai M, Jiang N, Fu W, Huang C, Tian L, Mi N, Gao L, Ma H, Lu Y, Cao J, Zhang C, Yue P, Zhang Y, Lin Y, Meng W, Li X. (2024). Establishment and characterization of a novel hilar cholangiocarcinoma cell line, CBC3T-1. Human Cell. 37(1): 364-375 |
Validation of Dual-Color Dual ISH for HER2/neu Gene in Breast Cancer Rathi A, Sahay A, Shet TM, Patil A, Desai SB. (2024). Validation of Dual-Color Dual In Situ Hybridization for HER2/neu Gene in Breast Cancer. Archives of Pathology & Laboratory Medicine. 148 (4): 453-460. |
What Is the Role of Macrophage-Derived Exosomes in Gastric Cancer Progression? Qiu Y, Lu G, Li N, Hu Y, Tan H, Jiang C. (2024). Exosome-mediated communication between gastric cancer cells and macrophages: implications for tumor microenvironment. Frontiers in Immunology. 15: 1327281. |
Dai Z, Cai R, Zeng H, Zhu H, Dou Y, Sun S. (2024). Exosomes may be the next generation of promising cell-free vaccines. Human Vaccines & Immunotherapeutics. 20 (1): 2345940. |
Cell Medicine Articles
2022 |
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Application of aCGH for Identification of Chromosomal Aberrations Kowalczyk K, Smyk M, Bartnik-Głaska M, Plaskota I, Wiśniowiecka-Kowalnik B, Bernaciak J, Chojnacka M, Paczkowska M, Niemiec M, Dutkiewicz D, Kozar A, Magdziak R, Krawczyk W, Pietras G, Michalak E, Klepacka T, Obersztyn E, Bal J, Nowakowska BA. (2022). Application of array comparative genomic hybridization (aCGH) for identification of chromosomal aberrations in the recurrent pregnancy loss. Journal of Assisted Reproduction and Genetics. 39 (2), 357-367. |
2023 |
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Rolles B, Ferreira MSV, Vieri M, Rheinwalt KP, Schmitz SM, Alizai PH, Neumann U, Brümmendorf TH, Beier F, Ulmer TF, Tometten M. (2023). Telomere length dynamics measured by flow-FISH in patients with obesity undergoing bariatric surgery. Scientific Reports. 13 (1), 304. |
Maalej KM, Merhi M, Inchakalody VP, Mestiri S, Alam M, Maccalli C, Cherif H, Uddin S, Steinhoff M, Marincola FM, Dermime S. (2023). CAR-cell therapy in the era of solid tumor treatment: current challenges and emerging therapeutic advances. Molecular Cancer. 22 (1), 20. |
Inactive Disease in Lupus Patients Normalizes Ifnα and B-Cell Subsets Bradford HF, Haljasmägi L, Menon M, McDonnell TCR, Särekannu K, Vanker M, Peterson P, Wincup C, Abida R, Gonzalez RF, Bondet V, Duffy D, Isenberg DA, Kisand K, Mauri C. (2023). Inactive disease in patients with lupus is linked to autoantibodies to type I interferons that normalize blood IFNα and B cell subsets. Cell Reports Medicine. 4 (1), 100894. |
Gerace D, Zhou Q, Kenty JH, Veres A, Sintov E, Wang X, Boulanger KR, Li H, Melton DA. (2023). Engineering human stem cell-derived islets to evade immune rejection and promote localized immune tolerance. Cell Reports Medicine. 4 (1), 100879. |
Khan E, Hasan I, Haque ME. (2023). Parkinson's Disease: Exploring Different Animal Model Systems. International Journal of Molecular Sciences. 24 (10), 9088. |
Chadwick W, Maudsley S, Hull W, Havolli E, Boshoff E, Hill MDW, Goetghebeur PJD, Harrison DC, Nizami S, Bedford DC, Coope G, Real K, Thiemermann C, Maycox P, Carlton M, Cole SL. (2023). The oDGal Mouse: A Novel, Physiologically Relevant Rodent Model of Sporadic Alzheimer's Disease. International Journal of Molecular Science.24 (8), 6953. |
Investigation of Simplified Physiologically-Based Pharmacokinetic Models Yau E, Olivares-Morales A, Ogungbenro K, Aarons L, Gertz M. (2023). Investigation of simplified physiologically-based pharmacokinetic models in rat and human. CPT Pharmacometrics and Systems Pharmacology. 12 (3), 333-345. |
Kim W, Kim E, Lee J, Song CH, Jung W, Shin S, Kim KB, Shin BS, Kim TH. (2023). Development of an LC-MS/MS Assay and Toxicokinetic Characterization of Hexamethylenetetramine in Rats. Toxics. 11 (4), 337. |
Qadir A, Samad DA, Asif M, Ali MM, Zain S. (2023). Investigating the effect of vandetanib and celecoxib combination on angiogenesis. Journal of Taibah University Medical Sciences. 18 (5), 1011-1017. |
Jimenez-Tellez N, Vera CD, Yildirim Z, Vicente Guevara J, Zhang T, Wu JC. (2023). Generation of two iPSC lines from long QT syndrome patients carrying SNTA1 variants. Stem Cell Research. 66: 103003. |
Generation of NRF2 Knockout iPSC Clones Using CRISPR/Cas9 Editing Merkert S, Haase A, Dahlmann J, Göhring G, Waqas FH, Pessler F, Martin U, Olmer R. (2023). Generation of two human NRF2 knockout iPSC clones using CRISPR/Cas9 editing. Stem Cell Research. 69: 103090. |
Assessment of MDPV Permeability Across the Caco-2 Monolayer Almeida AS, Silva B, Remião F, Fernandes C. (2023). Assessment of the Permeability of 3,4-Methylenedioxypyrovalerone (MDPV) across the Caco-2 Monolayer for Estimation of Intestinal Absorption and Enantioselectivity. International Journal of Molecular Sciences. 24 (3): 2680. |
A Novel in Vitro Model of Intestinal Epithelial Drug Permeability Cheng Y, Watanabe C, Ando Y, Kitaoka S, Egawa Y, Takashima T, Matsumoto A, Murakami M. (2023). Caco-2 Cell Sheet Partially Laminated with HT29-MTX Cells as a Novel In Vitro Model of Gut Epithelium Drug Permeability. Pharmaceutics. 15 (9): 2338. |
2024 |
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Huang Q, Chen X, Yu S, Gong G, Shu H. (2024). Research progress in brain-targeted nasal drug delivery. Frontiers in Aging Neuroscience. 15: 1341295. |
Lee J, Beers JL, Geffert RM, Jackson KD. (2024). A Review of CYP-Mediated Drug Interactions: Mechanisms and In Vitro Drug-Drug Interaction Assessment. Biomolecules. 14(1): 99. |
Solberg H, Bartholdy C, Landsy LH, Andresen LO. (2024). Stability of anti-drug antibodies in human serum samples. Journal of Immunological Methods. 525: 113616. |
Guo Q, Qian ZM. (2024). Macrophage-based drug delivery: Key challenges and strategies. Bioactive Materials. 38: 55-72. |
Increased Brain Uptake of Gentamicin and Ceftazidime under Isoflurane Anesthesia Ahn Y, Patil CD, Nozohouri E, Zoubi S, Patel D, Bickel U. (2024). Higher Brain Uptake of Gentamicin and Ceftazidime under Isoflurane Anesthesia Compared to Ketamine/Xylazine. Pharmaceutics. 16 (1): 135. |
Investigation of Pharmacokinetic DDI Between Olaparib and Metformin Stanisławiak-Rudowicz J, Karbownik A, Szkutnik-Fiedler D, Otto F, Grabowski T, Wolc A, Grześkowiak E, Szałek E. (2024). Bidirectional pharmacokinetic drug interactions between olaparib and metformin. Cancer Chemotherapy and Pharmacology. 93 (1): 79-88. |
Martinez Naya N, Kelly J, Corna G, Golino M, Polizio AH, Abbate A, Toldo S, Mezzaroma E. (2024). An Overview of Cannabidiol as a Multifunctional Drug: Pharmacokinetics and Cellular Effects. Molecules. 29 (2): 473. |
Exosome MicroRNA-22 Inhibiting Proliferation, Migration, and Invasion in OS Ruan Q, Wang C, Wu Y, Zhu Q. (2024). Exosome microRNA-22 inhibiting proliferation, migration, and invasion through regulating Twist1/CADM1 axis in osteosarcoma. Scientific Reports. 14 (1): 761. |
Disease Models - Related Articles
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Ennerfelt H, Frost EL, Shapiro DA, Holliday C, Zengeler KE, Voithofer G, Bolte AC, Lammert CR, Kulas JA, Ulland TK, Lukens JR. (2022). SYK coordinates neuroprotective microglial responses in neurodegenerative disease. Cell. 185 (22), 4135-4152. |
An Exosome-Related RNA Risk Model for Predicting Breast Cancer Qiu P, Guo Q, Lin J, Pan K, Chen J, Ding M. (2022). An exosome-related long non-coding RNAs risk model could predict survival outcomes in patients with breast cancer. Scientific Reports. 12(1), 22322. |
Inhibition of Lin28 Restores Lipid Homeostasis in Disease Models Lekka E, Kokanovic A, Mosole S, Civenni G, Schmidli S, Laski A, Ghidini A, Iyer P, Berk C, Behera A, Catapano CV, Hall J. (2022). Pharmacological inhibition of Lin28 promotes ketogenesis and restores lipid homeostasis in models of non-alcoholic fatty liver disease. Nature Communications. 13(1), 7940. |
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Maalej KM, Merhi M, Inchakalody VP, Mestiri S, Alam M, Maccalli C, Cherif H, Uddin S, Steinhoff M, Marincola FM, Dermime S. (2023). CAR-cell therapy in the era of solid tumor treatment: current challenges and emerging therapeutic advances. Molecular Cancer. 22 (1), 20. |
Zhang L, Chen W, Liu S, Chen C. (2023). Targeting Breast Cancer Stem Cells. International Journal of Biological Sciences. 19 (2), 552-570. |
In Vitro Cellular Reprogramming to Model Disorders of Sex Development Gonen N, Eozenou C, Mitter R, Elzaiat M, Stévant I, Aviram R, Bernardo AS, Chervova A, Wankanit S, Frachon E, Commère PH, Brailly-Tabard S, Valon L, Barrio Cano L, Levayer R, Mazen I, Gobaa S, Smith JC, McElreavey K, Lovell-Badge R, Bashamboo A. (2023). In vitro cellular reprogramming to model gonad development and its disorders. Science Advances. 9(1), eabn9793. |
Inactive Disease in Lupus Patients Normalizes Ifnα and B-Cell Subsets Bradford HF, Haljasmägi L, Menon M, McDonnell TCR, Särekannu K, Vanker M, Peterson P, Wincup C, Abida R, Gonzalez RF, Bondet V, Duffy D, Isenberg DA, Kisand K, Mauri C. (2023). Inactive disease in patients with lupus is linked to autoantibodies to type I interferons that normalize blood IFNα and B cell subsets. Cell Reports Medicine. 4 (1), 100894. |
Whitehouse C, Corbett N, Brownlees J. (2023). 3D models of neurodegeneration: implementation in drug discovery. Trends in Pharmacological Sciences. 44 (4), 208-221. |
Yuan J, Li X, Yu S. (2023). Cancer organoid co-culture model system: Novel approach to guide precision medicine. Frontiers in Immunology. 13: 1061388. |
Loewa A, Feng JJ, Hedtrich S. (2023). Human disease models in drug development. Nature Reviews Bioengineering. 11: 1-15. |
Animal Models of Diabetic Kidney Disease Luo W, Tang S, Xiao X, Luo S, Yang Z, Huang W, Tang S. (2023). Translation Animal Models of Diabetic Kidney Disease: Biochemical and Histological Phenotypes, Advantages and Limitations. Diabetes, Metabolic Syndrome, and Obesity. 16: 1297-1321. |
Corleis B, Bastian M, Hoffmann D, Beer M, Dorhoi A. (2023). Animal models for COVID-19 and tuberculosis. Frontiers in Immunology. 14: 1223260. |
Animal Models of Necrotizing Enterocolitis Lopez CM, Sampah MES, Duess JW, Ishiyama A, Ahmad R, Sodhi CP, Hackam DJ. (2023). Models of necrotizing enterocolitis. Seminars In Perinatology. 47(1): 151695 |
A Novel in Vitro Model of Intestinal Epithelial Drug Permeability Cheng Y, Watanabe C, Ando Y, Kitaoka S, Egawa Y, Takashima T, Matsumoto A, Murakami M. (2023). Caco-2 Cell Sheet Partially Laminated with HT29-MTX Cells as a Novel In Vitro Model of Gut Epithelium Drug Permeability. Pharmaceutics. 15 (9): 2338. |
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Şen B, Balcı-Peynircioğlu B. (2024). Cellular models in autoinflammatory disease research. Clinical and Translational Immunology. 13 (1): e1481. |
Sanfeliu C, Bartra C, Suñol C, Rodríguez-Farré E. (2024). New insights in animal models of neurotoxicity-induced neurodegeneration. Frontiers in Neuroscience. 17: 1248727. |
3D Multi-Cell-Type Liver Organoids of Non-alcoholic Fatty Liver Diseases Bronsard J, Savary C, Massart J, Viel R, Moutaux L, Catheline D, Rioux V, Clement B, Corlu A, Fromenty B, Ferron PJ. (2024). 3D multi-cell-type liver organoids: A new model of non-alcoholic fatty liver disease for drug safety assessments. Toxicology In Vitro. 94: 105728. |
Angom RS, Nakka NMR. (2024). Zebrafish as a Model for Cardiovascular and Metabolic Disease: The Future of Precision Medicine. Biomedicines. 12 (3): 693. |
Orthotopic and Metastatic Tumor Models for Preclinical Research Stribbling SM, Beach C, Ryan AJ. (2024). Orthotopic and metastatic tumor models in preclinical cancer research. Pharmacology & Therapeutics. 257: 108631. |
Zhang W, Wang S, Zhang H, Meng Y, Jiao S, An L, Zhou Z. (2024). Modeling human gastric cancers in immunocompetent mice. Cancer Biology & Medicine. 21 (7): 553-70. |
Guimarães RP, Resende MCS, Tavares MM, Belardinelli de Azevedo C, Ruiz MCM, Mortari MR. (2024). Construct, Face, and Predictive Validity of Parkinson's Disease Rodent Models. International Journal of Molecular Sciences. 25 (16): 8971. |