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- Histology Services
- Immunohistochemistry (IHC), Immunofluorescence (IF) Service
Services
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Cell Services
- Cell Line Authentication
- Cell Surface Marker Validation Service
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Cell Line Testing and Assays
- Toxicology Assay
- Drug-Resistant Cell Models
- Cell Viability Assays
- Cell Proliferation Assays
- Cell Migration Assays
- Soft Agar Colony Formation Assay Service
- SRB Assay
- Cell Apoptosis Assays
- Cell Cycle Assays
- Cell Angiogenesis Assays
- DNA/RNA Extraction
- Custom Cell & Tissue Lysate Service
- Cellular Phosphorylation Assays
- Stability Testing
- Sterility Testing
- Endotoxin Detection and Removal
- Phagocytosis Assays
- Cell-Based Screening and Profiling Services
- 3D-Based Services
- Custom Cell Services
- Cell-based LNP Evaluation
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Stem Cell Research
- iPSC Generation
- iPSC Characterization
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iPSC Differentiation
- Neural Stem Cells Differentiation Service from iPSC
- Astrocyte Differentiation Service from iPSC
- Retinal Pigment Epithelium (RPE) Differentiation Service from iPSC
- Cardiomyocyte Differentiation Service from iPSC
- T Cell, NK Cell Differentiation Service from iPSC
- Hepatocyte Differentiation Service from iPSC
- Beta Cell Differentiation Service from iPSC
- Brain Organoid Differentiation Service from iPSC
- Cardiac Organoid Differentiation Service from iPSC
- Kidney Organoid Differentiation Service from iPSC
- GABAnergic Neuron Differentiation Service from iPSC
- Undifferentiated iPSC Detection
- iPSC Gene Editing
- iPSC Expanding Service
- MSC Services
- Stem Cell Assay Development and Screening
- Cell Immortalization
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ISH/FISH Services
- In Situ Hybridization (ISH) & RNAscope Service
- Fluorescent In Situ Hybridization
- FISH Probe Design, Synthesis and Testing Service
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FISH Applications
- Multicolor FISH (M-FISH) Analysis
- Chromosome Analysis of ES and iPS Cells
- RNA FISH in Plant Service
- Mouse Model and PDX Analysis (FISH)
- Cell Transplantation Analysis (FISH)
- In Situ Detection of CAR-T Cells & Oncolytic Viruses
- CAR-T/CAR-NK Target Assessment Service (ISH)
- ImmunoFISH Analysis (FISH+IHC)
- Splice Variant Analysis (FISH)
- Telomere Length Analysis (Q-FISH)
- Telomere Length Analysis (qPCR assay)
- FISH Analysis of Microorganisms
- Neoplasms FISH Analysis
- CARD-FISH for Environmental Microorganisms (FISH)
- FISH Quality Control Services
- QuantiGene Plex Assay
- Circulating Tumor Cell (CTC) FISH
- mtRNA Analysis (FISH)
- In Situ Detection of Chemokines/Cytokines
- In Situ Detection of Virus
- Transgene Mapping (FISH)
- Transgene Mapping (Locus Amplification & Sequencing)
- Stable Cell Line Genetic Stability Testing
- Genetic Stability Testing (Locus Amplification & Sequencing + ddPCR)
- Clonality Analysis Service (FISH)
- Karyotyping (G-banded) Service
- Animal Chromosome Analysis (G-banded) Service
- AAV Biodistribution Analysis (RNA ISH)
- Molecular Karyotyping (aCGH)
- Droplet Digital PCR (ddPCR) Service
- Digital ISH Image Quantification and Statistical Analysis
- SCE (Sister Chromatid Exchange) Analysis
- Biosample Services
- Histology Services
- Exosome Research Services
- In Vitro DMPK Services
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In Vivo DMPK Services
- Pharmacokinetic and Toxicokinetic
- PK/PD Biomarker Analysis
- Bioavailability and Bioequivalence
- Bioanalytical Package
- Metabolite Profiling and Identification
- In Vivo Toxicity Study
- Mass Balance, Excretion and Expired Air Collection
- Administration Routes and Biofluid Sampling
- Quantitative Tissue Distribution
- Target Tissue Exposure
- In Vivo Blood-Brain-Barrier Assay
- Drug Toxicity Services
Immunohistochemistry (IHC), Immunofluorescence (IF) Service
By providing the high quality immunohistochemistry (IHC) and immunofluorescence (IF) services to customers for many years, Creative Bioarray will give you the best and most comprehensive service in regular and customized immunohistochemistry and immunofluorescence services. Our talented and experienced scientists have more than 10 years’ experience in tissue-based IHC and IF. They would work closely with you and provide high quality service for you in a short period.
IHC, by exploiting the principle of antibodies binding specifically to antigens in biological tissues, is a routine method to detect antigens in cells of a tissue section. It is widely used in the diagnosis of diseases including cancer, neurological disease, digestive disease, etc. Specific molecular markers have been found and verified to be characteristic of particular cellular events in disease such as proliferation, apoptosis and inflammation. Thus it could be used in detection of such changes involved in disease. IHC is also a common method in basic research of disease to help understanding the distribution and localization of biomarkers and differentially expression of proteins in different parts of tissue. Creative Bioarray offers a comprehensive IHC service from project design, marker selection to image completion and data analysis. We are dedicated to satisfied every customer and assist them to achieve their specific research goals.
Creative Bioarray provides the routine and customized IHC and IF service:
- Preparation of Tissue Sections
We accept shipment of formalin-fixed tissues or cell samples. Following embedment would be performed. - Frozen Embedding and Sectioning
- Paraffin Embedding and Sectioning
- Cell Pellet Embedding and Sectioning
- Selection of Antibodies
We offer common biomarkers and staining, which includes, but not limited to: - H&E Staining
- Ki67+ (Cell proliferation)
- TUNEL (Cell apoptosis)
- CD15 (Hodgkin’s Disease)
- CD117 (Gastrointestinal stromal tumors)
- Cytokeratins (Carcinomas)
- CD10 (Renal cell carcinoma and acute lymphoblastic leukemia)
- CD20 (B-cell lymphomas)
- CD3 (T-cell lymphomas)
- Matrix metalloproteinase 9 (Carcinomas)
- PCNA (Carcinomas)
- CA-15-3 (Breast Tumor)
Our service is not just limited to these biomarkers. Other markers such as CD30, CD14, CD8, CD10, CD31, CD117, CEA, Desmin, P63, S-100, PSA, Mart-1 and more antibodies are also available. Please contact our agents for more information. Moreover, customers can also ship their own antibodies to us for use of the IHC service.
Zhang Y, Emilie V, Zhang M, et al. Scientific Reports, 2016, 6.
- Staining
We perform IHC and IF staining on slides with IHC single label or IHC and IF double label. IHC and IF double label staining present two markers on the same tissue slides, contributes to a better understanding of protein localization and interaction.
- Report and Analysis
- Pathological evaluation including scoring and analysis
- High-resolution digital imaging
- Spot counting and other image analysis
- Pathology consultation
Creative Bioarray is a reliable company providing routine and customized IHC and IF service. We have excellent scientists who have more than 10 years’ experience in IHC and IF staining. They work closely with you on every step from antibody selection to image analysis. We promise the quality and speed of our service, and we guarantee the satisfaction of our customers.
Explore Other Options
For research use only. Not for any other purpose.