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- Dermatology
- Skin Irritation
Applications
-
Cell Services
- Cell Line Authentication
- Cell Surface Marker Validation Service
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Cell Line Testing and Assays
- Toxicology Assay
- Drug-Resistant Cell Models
- Cell Viability Assays
- Cell Proliferation Assays
- Cell Migration Assays
- Soft Agar Colony Formation Assay Service
- SRB Assay
- Cell Apoptosis Assays
- Cell Cycle Assays
- Cell Angiogenesis Assays
- DNA/RNA Extraction
- Custom Cell & Tissue Lysate Service
- Cellular Phosphorylation Assays
- Stability Testing
- Sterility Testing
- Endotoxin Detection and Removal
- Phagocytosis Assays
- Cell-Based Screening and Profiling Services
- 3D-Based Services
- Custom Cell Services
- Cell-based LNP Evaluation
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Stem Cell Research
- iPSC Generation
- iPSC Characterization
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iPSC Differentiation
- Neural Stem Cells Differentiation Service from iPSC
- Astrocyte Differentiation Service from iPSC
- Retinal Pigment Epithelium (RPE) Differentiation Service from iPSC
- Cardiomyocyte Differentiation Service from iPSC
- T Cell, NK Cell Differentiation Service from iPSC
- Hepatocyte Differentiation Service from iPSC
- Beta Cell Differentiation Service from iPSC
- Brain Organoid Differentiation Service from iPSC
- Cardiac Organoid Differentiation Service from iPSC
- Kidney Organoid Differentiation Service from iPSC
- GABAnergic Neuron Differentiation Service from iPSC
- Undifferentiated iPSC Detection
- iPSC Gene Editing
- iPSC Expanding Service
- MSC Services
- Stem Cell Assay Development and Screening
- Cell Immortalization
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ISH/FISH Services
- In Situ Hybridization (ISH) & RNAscope Service
- Fluorescent In Situ Hybridization
- FISH Probe Design, Synthesis and Testing Service
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FISH Applications
- Multicolor FISH (M-FISH) Analysis
- Chromosome Analysis of ES and iPS Cells
- RNA FISH in Plant Service
- Mouse Model and PDX Analysis (FISH)
- Cell Transplantation Analysis (FISH)
- In Situ Detection of CAR-T Cells & Oncolytic Viruses
- CAR-T/CAR-NK Target Assessment Service (ISH)
- ImmunoFISH Analysis (FISH+IHC)
- Splice Variant Analysis (FISH)
- Telomere Length Analysis (Q-FISH)
- Telomere Length Analysis (qPCR assay)
- FISH Analysis of Microorganisms
- Neoplasms FISH Analysis
- CARD-FISH for Environmental Microorganisms (FISH)
- FISH Quality Control Services
- QuantiGene Plex Assay
- Circulating Tumor Cell (CTC) FISH
- mtRNA Analysis (FISH)
- In Situ Detection of Chemokines/Cytokines
- In Situ Detection of Virus
- Transgene Mapping (FISH)
- Transgene Mapping (Locus Amplification & Sequencing)
- Stable Cell Line Genetic Stability Testing
- Genetic Stability Testing (Locus Amplification & Sequencing + ddPCR)
- Clonality Analysis Service (FISH)
- Karyotyping (G-banded) Service
- Animal Chromosome Analysis (G-banded) Service
- AAV Biodistribution Analysis (RNA ISH)
- Molecular Karyotyping (aCGH)
- Droplet Digital PCR (ddPCR) Service
- Digital ISH Image Quantification and Statistical Analysis
- SCE (Sister Chromatid Exchange) Analysis
- Biosample Services
- Histology Services
- Exosome Research Services
- In Vitro DMPK Services
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In Vivo DMPK Services
- Pharmacokinetic and Toxicokinetic
- PK/PD Biomarker Analysis
- Bioavailability and Bioequivalence
- Bioanalytical Package
- Metabolite Profiling and Identification
- In Vivo Toxicity Study
- Mass Balance, Excretion and Expired Air Collection
- Administration Routes and Biofluid Sampling
- Quantitative Tissue Distribution
- Target Tissue Exposure
- In Vivo Blood-Brain-Barrier Assay
- Drug Toxicity Services
Skin Irritation
The potential of chemicals to induce skin irritation is an important consideration in establishing procedures for the safe handling, packing and transport of chemicals. Skin irritation testing becomes an important requisite of the preparation of pharmaceuticals and cosmetics. As an alternative to the animal-based Skin Irritation Test, Skin irritation potential can be predicted by in vitro systems, provided they are sufficiently complex to mimic skin barrier in vivo and cell reactivity.
Your needs
- You are looking for a skin model to perform skin irritation testing?
- You wish to screen ingredients, and characterize the efficacy or toxicity or safety of any products or chemicals?
- You'd like to find a customized service of skin irritation?
Our Capability
Creative Bioarray provides in vitro systems for skin irritation assays including skin models and in vitro testing services to our customer utilized by the cosmetics, personal care, household products, chemical, pharmaceutical, and biotech industries.
Model
Reconstructed human epidermis (RHE)
Irritation testing
Creative Bioarray's skin irriation test is preformed using our or the customer's Reconstructed human epidermis (RHE) based on the OECD Test guidelines 439 which were published in 2010. Creative Bioarray follows the standardised skin irritation test procedure within the OECD guidelines.
Our Strength
- Our RHE model closely mimics human epidermis
- Our skin irritation test results provide a robust assessment of skin irritation
Result example
Fig1. Cell viability measured by MTT assay after treatment of cells with different compounds.
Related Products and Services
Choose our models to perform screening assays in house, or choose our assays and services directly!!
- Reconstructed human epidermis (RHE)
- Ex vivo skin explants
- Compound screening service
Our customer service representatives are available 24hr a day! We thank you for choosing Creative Bioarray services!
In vitro Skin Models:
Explore Other Options
For research use only. Not for any other purpose.
