Services
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Cell Services
- Cell Line Authentication
- Cell Surface Marker Validation Service
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Cell Line Testing and Assays
- Toxicology Assay
- Drug-Resistant Cell Models
- Cell Viability Assays
- Cell Proliferation Assays
- Cell Migration Assays
- Soft Agar Colony Formation Assay Service
- SRB Assay
- Cell Apoptosis Assays
- Cell Cycle Assays
- Cell Angiogenesis Assays
- DNA/RNA Extraction
- Custom Cell & Tissue Lysate Service
- Cellular Phosphorylation Assays
- Stability Testing
- Sterility Testing
- Endotoxin Detection and Removal
- Phagocytosis Assays
- Cell-Based Screening and Profiling Services
- 3D-Based Services
- Custom Cell Services
- Cell-based LNP Evaluation
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Stem Cell Research
- iPSC Generation
- iPSC Characterization
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iPSC Differentiation
- Neural Stem Cells Differentiation Service from iPSC
- Astrocyte Differentiation Service from iPSC
- Retinal Pigment Epithelium (RPE) Differentiation Service from iPSC
- Cardiomyocyte Differentiation Service from iPSC
- T Cell, NK Cell Differentiation Service from iPSC
- Hepatocyte Differentiation Service from iPSC
- Beta Cell Differentiation Service from iPSC
- Brain Organoid Differentiation Service from iPSC
- Cardiac Organoid Differentiation Service from iPSC
- Kidney Organoid Differentiation Service from iPSC
- GABAnergic Neuron Differentiation Service from iPSC
- Undifferentiated iPSC Detection
- iPSC Gene Editing
- iPSC Expanding Service
- MSC Services
- Stem Cell Assay Development and Screening
- Cell Immortalization
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ISH/FISH Services
- In Situ Hybridization (ISH) & RNAscope Service
- Fluorescent In Situ Hybridization
- FISH Probe Design, Synthesis and Testing Service
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FISH Applications
- Multicolor FISH (M-FISH) Analysis
- Chromosome Analysis of ES and iPS Cells
- RNA FISH in Plant Service
- Mouse Model and PDX Analysis (FISH)
- Cell Transplantation Analysis (FISH)
- In Situ Detection of CAR-T Cells & Oncolytic Viruses
- CAR-T/CAR-NK Target Assessment Service (ISH)
- ImmunoFISH Analysis (FISH+IHC)
- Splice Variant Analysis (FISH)
- Telomere Length Analysis (Q-FISH)
- Telomere Length Analysis (qPCR assay)
- FISH Analysis of Microorganisms
- Neoplasms FISH Analysis
- CARD-FISH for Environmental Microorganisms (FISH)
- FISH Quality Control Services
- QuantiGene Plex Assay
- Circulating Tumor Cell (CTC) FISH
- mtRNA Analysis (FISH)
- In Situ Detection of Chemokines/Cytokines
- In Situ Detection of Virus
- Transgene Mapping (FISH)
- Transgene Mapping (Locus Amplification & Sequencing)
- Stable Cell Line Genetic Stability Testing
- Genetic Stability Testing (Locus Amplification & Sequencing + ddPCR)
- Clonality Analysis Service (FISH)
- Karyotyping (G-banded) Service
- Animal Chromosome Analysis (G-banded) Service
- AAV Biodistribution Analysis (RNA ISH)
- Molecular Karyotyping (aCGH)
- Droplet Digital PCR (ddPCR) Service
- Digital ISH Image Quantification and Statistical Analysis
- SCE (Sister Chromatid Exchange) Analysis
- Biosample Services
- Histology Services
- Exosome Research Services
- In Vitro DMPK Services
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In Vivo DMPK Services
- Pharmacokinetic and Toxicokinetic
- PK/PD Biomarker Analysis
- Bioavailability and Bioequivalence
- Bioanalytical Package
- Metabolite Profiling and Identification
- In Vivo Toxicity Study
- Mass Balance, Excretion and Expired Air Collection
- Administration Routes and Biofluid Sampling
- Quantitative Tissue Distribution
- Target Tissue Exposure
- In Vivo Blood-Brain-Barrier Assay
- Drug Toxicity Services
Disease Models
Efficacy studies of lead candidates in animal disease models are crucial for the selection of preclinical candidates in drug discovery. Creative Bioarray has established a diverse array of rodent and non-human primate (NHP) disease models, encompassing cardiovascular disease models, metabolic disease models, neurological disease models, oncology models, and more. We offer validated and custom in vivo disease modeling services tailored to our clients' specific needs. Our extensive collection of animal-based disease models, representing various organ systems, enables our clients to select the most suitable models for testing promising compounds and optimizing lead candidates. Our commitment to providing high-quality, reliable disease models ensures that our clients can conduct their efficacy studies with confidence, advancing their drug discovery projects towards successful clinical translation.
Oncology Models
Neurological Disease Models
- Alzheimer's disease
- Seizure
- Parkinson's disease
- Ischemic Stroke Model
- Acute Spinal Cord Injury (ASCI) Model
- Traumatic Brain Injury (TBI) Model
- Hypoxic-Ischemic Encephalopathy (HIE) Model
- Tourette Syndrome (TS) Model
- Amyotrophic Lateral Sclerosis (ALS) Model
- Huntington’s Disease Model
- Intracerebral Hemorrhage (ICH) Models
Digestive Disease Models
Cardiovascular Disease Models
- Surgical models
- Animal models of hypertension
- DOCA-salt model
- Spontaneously hypertensive rat model
- Two-kidney-one-clip (2K1C) renovascular hypertension model
- Venous thrombosis model
- Atherosclerosis model
- Cardiac arrhythmia model
- Hyperlipoidemia model
- Drug-induced heart failure model
- Arterial Thrombosis Model
- Pulmonary Arterial Hypertension (PAH) Model
Liver Disease Models
- Alcoholic liver disease model
- Liver fibrosis model
- Acute liver injury
- Chronic liver injury
- Chronic fatty liver disease
- Alcoholic steatohepatitis (ASH) & non-Alcoholic steatohepatitis (NASH)
Metabolic Disease Models
- Type 1 diabetes mellitus model
- Type 2 diabetes mellitus model
- Animal model of hyperuricemia
- Nonalcoholic fatty liver disease (NASH) model
- High fat diet-induced obesity model
- Dyslipidemia
- Obesity
- Organ damage (UUO, CKD)
Respiratory Disease Models
Ocular Disease Models
- Inflammatory disorders
- Eye irritation
- Retinopathy of prematury
- Stromal ulceration
- Corneal graft
- Infectious keratitis
- Diabetic retinopathy
Inflammation & Autoimmune Disease Models
- Rheumatoid arthritis models
- Nephritis models
- Multiple sclerosis (MS) models
- Ocular inflammation models
- Sjögren's syndrome model
- LPS-induced acute lung injury model
- Peritonitis models
- Passive cutaneous anaphylaxis model
- Delayed-type hypersensitivity models
- Inflammatory bowel disease models
- Systemic lupus erythematosus animal models
- Oral mucositis model
- Asthma model
- Sepsis model
- Psoriasis model
- Atopic dermatitis (AD) model
- Scleroderma model
- Gouty arthritis model
- Carrageenan-Induced Air Pouch Synovitis Model
- Carrageenan-Induced Paw Edema Model
- Experimental Autoimmune Myasthenia Gravis (EAMG) Model
- Graft-versus-host Disease (GvHD) Model
Orthopedic Disease Models
Urology Disease Models
Rare Disease Models
- Huntington's disease
- Amyotrophic lateral sclerosis (ALS)
- Batten disease
- Multiple sclerosis (MS)
- Systemic lupus erythematosus (SLE)
- Muscular dystrophy
Pain Models
Surgical Models
- Cisterna magna cannulation
- Bile duct cannulation
- Portal vein cannulation
- Thoracic duct cannulation
- Intraduodenally administration
Skin Disease Models
- Hair Growth Models
- Wound Healing Models
- Acne Models
- Skin Photoaging Model
Infectious Disease Models
Reproductive Disease Models
Otology Disease Models
NHP Neurological Disease Models
- NHP Parkinson's Disease (PD) Model
- NHP Alzheimer's Disease (AD) Model
- NHP Ischemic Stroke Model
- NHP Intracerebral Hemorrhagic Stroke Model
- NHP Spinal Cord Injury (SCI) Model
- NHP Epilepsy Model
NHP Cardiovascular Disease Models
- NHP Myocardial Infarction Model
- NHP Hypertension Model
- NHP Atherosclerosis Model
- NHP Pulmonary Arterial hypertension (PAH) Model
- NHP Thrombosis Model
NHP Metabolic Disease Models
- NHP Obesity Model
- NHP Type I Diabetes Model
- NHP Type II Diabetes Model
- NHP Hyperuricemia Model
- NHP Acute Liver Failure Model
- NHP Liver Firosis Model
- NHP Alcoholic Fatty Liver Disease Model
- NHP Nonalcoholic Fatty Liver Disease (NAFLD) Model
NHP Respiratory Disease Models
- NHP Asthma Model
- NHP Acute Lung Injury Model
- NHP Idiopathic Pulmonary Fibrosis (IPF) Model
- NHP Chronic Obstructive Pulmonary Disease (COPD) Model
NHP Ocular Disease Models
- NHP Dry Eye Model
- NHP Glaucoma Model
- NHP Myopia Model
- NHP Uveitis Model
- NHP Diabetic Retinopathy (DR) Model
- NHP Age-related Macular Degeneration (AMD) Model
NHP Inflammation & Autoimmune Disease Models
- NHP Rheumatoid Arthritis (RA) Model
- NHP Osteoarthritis (OA) Model
- NHP Inflammatory Bowel Disease (IBD) Model
- NHP Delayed-type Hypersensitivity (DTH) Model
- NHP Psoriasis Model
- NHP Atopic Dermatitis (AD) Model
- NHP Multiple Sclerosis (MS) Model
- NHP Mucositis Model
- NHP Systemic Inflammation Model
NHP Urology Disease Models
- NHP Diabetic Nephropathy Model
- NHP Nephritis Model
NHP Orthopedic Disease Models
- NHP Osteoarthritis (OA) Model
- NHP Osteoporosis Model
Each of our meticulously crafted disease models is designed to elucidate specific aspects of drug properties and their mechanisms of action. Furthermore, the animals utilized in these studies are sourced from reputable, certified suppliers, ensuring the highest standards of animal welfare. All study protocols and animal use are rigorously reviewed and approved by the Institutional Animal Care and Use Committee (IACUC), adhering to strict ethical guidelines and regulatory requirements. By leveraging our comprehensive capabilities, our customers can significantly accelerate their drug discovery projects, facilitating a more efficient and effective translation from preclinical research to clinical development. Our commitment to providing a robust and ethically sound research environment ensures that our customers can advance their therapeutic candidates with confidence, ultimately contributing to the discovery of life-changing treatments.
If you are interested in our services, we invite you to reach out for more detailed information regarding the disease models we offer. Whether you are looking to gain insights into specific models or are interested in customizing a new model tailored to your unique research requirements, we are here to assist you.
Please don't hesitate to contact us to explore our comprehensive capabilities and services. Our team is ready to answer any questions you may have and provide guidance to help you find the best solutions for your research needs. You can also submit a direct inquiry to us, and we will respond promptly to ensure you receive the information you need. We look forward to collaborating with you to advance your research objectives
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For research use only. Not for any other purpose.
