RAMOS

Cat.No.: CSC-C1015

Species: Homo sapiens, human

Source: Lymph

Morphology: Lymphoblast

Culture Properties: Suspension

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Cat.No.

CSC-C1015

Description

Derived from a Burkitt's lymphoma which does not possess the EBV genome. EBV infectability and permanent conversion into EBV positive sub-lines is possible by in vitro infection. The cells have B lymphocyte characteristics, with surface associated mu and kappa chains.

Species

Homo sapiens, human

Source

Lymph

Recommended Medium

90% RPMI-1640 + 10% h.i. FBS

Culture Properties

Suspension

Morphology

Lymphoblast

STR DNA Profile

Amelogenin: X
CSF1PO: 10,11
D13S317: 13,14
D16S539: 10,13
D5S818: 7,12
D7S820: 11
THO1: 7,9.3
TPOX: 8,9
vWA: 15,16

Karyotype

Human hypodiploid karyotype; 45(44-46)<2n>X, -Y, del(2)(p16p23), t(8;14)(q24;q32.2), add(14)(p11), der(16)t(7;16)(q11.2;p13.2), der(17)t(13;17)(q33;p11.3)t(13;3)(q13;q?25), del(20)(q12); carries t(8;14) effecting IGH@-MYC rearrangement

Disease

a Burkitt's lymphoma

Quality Control

Mycoplasma: contamination was eliminated with ciprofloxacin (Ciprobay), then negative in microbiological culture, PCR assays
Immunology: CD3 -, CD10 +, CD13 -, CD19 +, CD20 +, CD34 -, CD37 +, CD38 +, cyCD79a +, CD80 +, CD138 -, HLA-DR +, sm/cyIgG -, sm/cy

Storage and Shipping

liquid nitrogen vapor phase

Citation Guidance

If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.

How cell culture is used in cancer research?

Cancer cell lines are widely used in biomedical research; they provide excellent model systems to study mechanisms associated with cancer development, thereby improving the understanding of cancer cell biology. Furthermore, these cell lines are used for the development and screening of novel anticancer drugs.

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