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Human Small Airway Epithelial Cells-Asthma
Cat.No.: CSC-C8074L
Species: Human
Source: Lung
Cell Type: Epithelial
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Asthma is an inflammatory disorder of the airways, which causes attacks of wheezing, shortness of breath, chest tightness, and coughing in patients. Degrees of severity are unique to individual patients as are responses to drug treatments. Adhesion of eosinophils to bronchial epithelial cells, and the interaction of airway smooth muscle and sub-epithelial fibroblasts play a critical role in asthma pathology. During an asthma attack bronchiole smooth muscle tissue can constrict and decrease the flow of air in the airways. The amount of air flow can further be decreased by inflammation or excess mucus secretion.
Applications:
Gene ex
Phenotypic changes to compounds
Transfect diseased cells
Co-culture with immune cells
Airway remodeling studies
Cellular interactions
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Cell Features:
HSMC are cryopreserved as secondary cells, e.g. cells are isolated from the stated tissue and expanded in culture vessels twice before cryopreservation.
HAoSMC are isolated from human aorta (ascending and/or descending).
HPASMC are isolated from human pulmonary artery.
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HBTSMC are isolated from the trachea and primary bronchi.
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HSMC are extensively tested to meet quality standards and exhibit optimal performance.
Creative Bioarray guarantees performance and quality.
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