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Human Small Airway Epithelial Cells-Asthma
Cat.No.: CSC-C8074L
Species: Human
Source: Lung; Airway
Cell Type: Epithelial Cell
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Asthma is an inflammatory disorder of the airways, which causes attacks of wheezing, shortness of breath, chest tightness, and coughing in patients. Degrees of severity are unique to individual patients as are responses to drug treatments. Adhesion of eosinophils to bronchial epithelial cells, and the interaction of airway smooth muscle and sub-epithelial fibroblasts play a critical role in asthma pathology. During an asthma attack bronchiole smooth muscle tissue can constrict and decrease the flow of air in the airways. The amount of air flow can further be decreased by inflammation or excess mucus secretion.
Applications:
Gene ex
Phenotypic changes to compounds
Transfect diseased cells
Co-culture with immune cells
Airway remodeling studies
Cellular interactions
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Description: Human Pulmonary Artery Smooth Muscle Cells (HPASMCs) provided by Creative Bioarray are isolated from the normal human pulmonary artery tissue. The cells are cryopreserved at passage 2 and delivered frozen. Each vial contains more than 0.5*10^6 viable cells after thawing. The cells are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HPASMCs are guaranteed for at least 12 population doublings under the conditions provided by Creative Bioarray. Repeated freezing and thawing of cells is not recommended.
Description: Creative Bioarray's normal Human Lung Smooth Muscle Cells, when grown in SMC Medium, provide an ideal culture model for the study of angiogenesis, atherosclerosis, diabetes or vascular/pulmonary biology.
Cell Features:
HSMC are cryopreserved as secondary cells, e.g. cells are isolated from the stated tissue and expanded in culture vessels twice before cryopreservation.
HAoSMC are isolated from human aorta (ascending and/or descending).
HPASMC are isolated from human pulmonary artery.
HCASMC are isolated from human coronary arteries.
HLMSC are isolated from the lobes of the lungs.
HBTSMC are isolated from the trachea and primary bronchi.
HSMC can be grown without phenol red or antimicrobials when cultured in VascuLife SMC Medium.
HSMC are extensively tested to meet quality standards and exhibit optimal performance.
Creative Bioarray guarantees performance and quality.
Description: Creative Bioarray's normal Human Lung Fibroblasts provide an ideal cell system to establish serum free human feeder layers for human embryonic stem cell cultures or as a model to study wound healing, toxicology or basic cell biology.
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