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ARPE-19
Cat.No.: CSC-C9083W
Species: Human
Source: Eye
Morphology: epithelial
Cell Type: Epithelial
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Cat.No.
CSC-C9083W
Description
this is a spontaneously arising retinal pigment epithelia (RPE) cell line derived from the normal eyes of 19-year-old male who died from head trauma in a motor vehicle accident; the cells form stable monolayers, which exhibit morphological and functional polarity; the line expresses the RPE-specific markers CRALBP and RPE-65; the cells exhibit morphological polarization when plated on laminin-coated Transwell-COL filters in medium with a low serum concentration; they form tight-junctions with transepithelial resistance of monolayers reaching a maximum of 50 to 100 ohms/cm2 after 4 weeks of culture; the cells are diploid and can be carried for over 30 passages.
Species
Human
Source
Eye
Recommended Medium
Morphology
epithelial
Cell Type
Epithelial
Disease
Normal
Storage and Shipping
liquid nitrogen vapor phase
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