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ISH/FISH Services
- In Situ Hybridization (ISH) & RNAscope Service
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FISH Applications
- Multicolor FISH (M-FISH) Analysis
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- Transgene Mapping (Locus Amplification & Sequencing)
- Stable Cell Line Genetic Stability Testing
- Genetic Stability Testing (Locus Amplification & Sequencing + ddPCR)
- Clonality Analysis Service (FISH)
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In Vivo DMPK Services
- Pharmacokinetic and Toxicokinetic
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- Bioanalytical Package
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ISH/FISH
In situ hybridization (ISH) and fluorescence in situ hybridization (FISH) techniques offer powerful methods for analyzing gene expression and localization within tissues and cells. Creative Bioarray offers ISH/FISH resources, to help our customers explore to identify and localize specific nucleic acid sequences within tissues and cells.
Multiple Options for Proving Monoclonality
Tag: FISH
Details: In recent years, proof of clonality has become a focus of attention for regulatory agencies. Clonality is thought to minimize cell bank heterogeneity, resulting in the consistent production of products.
Multiple Approaches to Karyotyping
Tag: FISH
Details: Karyotypes are prepared using standardized staining procedures that reveal characteristic structural features for each chromosome.
Telomere Length Measurement Methods
Tag: FISH
Details: Telomeres are highly conserved tandem nucleotide repeats that include proximal double-stranded and distal single-stranded regions.
Comparative Genomic Hybridization and Its Applications
Tag: FISH
Details: Comparative genomic hybridization (CGH) is a technique that permits the detection of chromosomal copy number changes without the need for cell culturing.
In Situ Hybridization Probes
Tag: ISH
Details: The landscape of ISH probes encompasses a diverse array of probe types tailored to address distinct research requirements. DNA probes, RNA probes, and modified nucleic acid probes constitute the major categories.
RNAscope ISH Technology
Tag: ISH
Details: Launched in 2012, RNAscope is a novel RNA in situ hybridization (ISH) technology that detects target RNAs in tissues and cells.
Whole Chromosome Painting Probes for FISH
Tag: FISH
Details: Whole chromosome painting probes play a crucial role in FISH by enabling the simultaneous visualization of entire chromosomes, providing valuable insights into the structural organization and behavior of chromosomes.
Different Types of FISH Probes for Oncology Research
Tag: FISH
Details: Oncology fluorescence in situ hybridization (FISH) probes represent a groundbreaking molecular cytogenetic technique that has revolutionized cancer research, diagnosis, and personalized medicine.
Overview of Common FISH Techniques
Tag: FISH
Details: The versatility of FISH has led to the development of several specialized techniques tailored to specific research needs.
Mapping of Transgenes by FISH
Tag: FISH
Details: The mapping of transgenes by fluorescence in situ hybridization (FISH) represents a pivotal technique in molecular cytogenetics.
Comprehensive Comparison of IHC, CISH, and FISH Techniques
Tag: FISH
Details: Immunohistochemistry (IHC), chromogenic in situ hybridization (CISH), and fluorescence in situ hybridization (FISH) are pivotal techniques in life sciences.
Reagents Used in FISH Experiments
Tag: FISH
Details: With a focus on precision and reliability, we offer a comprehensive range of specialized reagents essential for the visualization and analysis of specific DNA sequences within biological samples.
What Is the Use of FISH in Solid Tumors?
Tag: FISH
Details: FISH, with its ability to visualize specific genetic abnormalities within individual cells, has revolutionized our understanding of solid tumors and paved the way for improved diagnosis and targeted therapies.
Small RNA Detection by ISH Methods
Tag: ISH
Details: In situ hybridization (ISH) methods provide powerful tools for visualizing and studying small RNA molecules within cells and tissues.
What Types of Multicolor FISH Probe Sets Are Available?
Tag: FISH
Details: Multicolor FISH (mFISH) overcomes several limitations by employing a combination of fluorescently labeled probes.
CARD-FISH: Illuminating Microbial Diversity
Tag: FISH
Details: CARD-FISH is a powerful technique that enables the visualization and identification of microbial cells in their natural environment.
Guidelines for the Design of FISH Probes
Tag: FISH
Details: The probe design/selection is one of the most important factors in the successful performance of FISH. The selection of the optimal probe must take into account several parameters.
FISH Tips and Troubleshooting
Tag: FISH
Details: When embarking on a FISH experiment, meticulous planning and execution are crucial for obtaining reliable and reproducible results.
Differences Between DNA and RNA Probes
Tag: ISH
Details: The main differences, types and applications of DNA and RNA probes in ISH.
What are Single, Dual, and Multiplex ISH?
Tag: ISH
Details: An introduction to single, dual, and multiplex ISH techniques and applications, including their progress and utility in detecting specific nucleic acid sequences in cell or tissue samples.
How to Choose Markers for ISH Probes？
Tag: ISH
Details: This article explores different probe markers, highlighting their distinct advantages and disadvantages, and considerations for choosing the most suitable method.
FISH techniques for biofilm detection
Tag: ISH
Details: The types, characteristics and advantages of FISH techniques for biofilm detection were summarized.
Overview of Oligo-FISH Technology
Tag: FISH
Details: This article provides an in-depth overview of the Oligo-FISH technology, its principles, advantages, limitations, and applications in plant genome research
What are the differences between FISH, aCGH, and NGS?
Tag: FISH
Details: Each of the technologies discussed—FISH, aCGH, and NGS—presents its own distinct advantages and limitations.
How to Use FISH in Hematologic Neoplasms?
Tag: FISH
Details: FISH technology has become an indispensable part of precision medicine in hematological oncology due to its accuracy and speed in detecting small gene mutations
For research use only. Not for any other purpose.
