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T3M-1 Cl-10
Cat.No.: CSC-C6429J
Species: Human
Morphology: epithelial-like
Culture Properties: Adherent cells
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Store in liquid nitrogen.
The SRB assay possesses a nondestructive and indefinitely stable colorimetric endpoint and the color development is rapid and stable and is readily measured at absorbance between 560 and 580nm.
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Average Rating: 5.0 | 1 Scientist has reviewed this product
Suitable
The ease of handling and culturing the tumor cell products has made it suitable for researchers at various levels of expertise.
03 Oct 2022
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Description: The CAL-27 cells are established from the poorly differentiated squamous cell carcinoma of the tongue removed from a 56-year-old man before treatment in 1982. CAL 27 cells are epithelial, polygonal with a highly granular cytoplasm. Immunocytochemical studies show strong positive staining with anti keratin antibodies. The cells do not grow well in semi-solid medium. Marked inhibition of thymidine incorporation was observed in the presence of VP16 (etoposide), CCNU (1-[2-chloroethyl]-3-cyclohexyl-1-nitrosourea), VM26 (teniposide), ADM (adriamycin), CPA (cyclophosphamide), and MTX (methotrexate). CAL 27 cells were resistant to treatment with VDS (vindesine sulfate), CDP (cis-platinum) or ACTD (actinomycin D).
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Description: The FaDu cell line which is from a squamous cell carcinoma of the hypopharynx and established from a patient from Calcutta, India. The cell line has a population doubling time of approximately 50 hours. Ultrastructural observation reveals the presence of bundles of tonofilaments in the cells and desmonsomal regions distributed at the boundaris of adjacent cells. The cell line is susceptible to infection by some RNA- and DNA-containing viruses.
Description: The ES-2 cell line was established from a surgical tumor specimen taken from a 47 year old black woman. This cell line was isolated from a poorly differentiated ovarian clear cell carcinoma.Initially, the cells were grown in soft agar.The cells exhibit low to moderate resistance to a number of chemotherapeutic agents including doxorubicin, cisplatin, carmustine, etoposide and cyanomorpholinodoxorubicin (MRA-CN). ES-2 cells express low levels of P glycoprotein.
