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The development of tumor cells is driven by genetic mutations and alterations in key cellular processes, including cell cycle regulation, DNA repair mechanisms, and signaling pathways involved in cell growth and survival. Environmental factors and lifestyle choices can also contribute to tumor formation.
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Average Rating: 4.0 | 1 Scientist has reviewed this product
No contamination
Cells from Creative Bioarray are not contaminated, so we can get reliable and reproducible results.
25 June 2023
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Description: FTC-133 was isolated from a lymph node metastasis of a follicular thyroid carcinoma. The morphology differs from flat polygonal to spindle formed cells. They retained differentiated thyrocyte function and thyrocyte responsiveness to thyrotropin and local active growth factors. Thyroglobulin immunoreactivity could be shown in the cytoplasm and EGF receptor immunoreactivity could be visualised on the cell membranes. Complex chromosomal changes were detected as well as a p53 mutation.
Description: Species: human male 42 years old;
Tissue: thyroid;
Tumor: carcinoma, follicular;
Derived from: lung metastasis
Description: Established from the primary tumor of a 67-year-old woman with primary thyroid carcinoma (undifferentiated carcinoma, composed of spindle, polygonal and giant cells)
Description: Established from the sarcoma of the thyroid gland from a 47-year-old woman in 1985
Description: Established from the tumor tissue of a 76-year-old woman with metastasizing papillary thyroid carcinoma in 1992
