8305C

Cat.No.: CSC-C0290

Species: Human

Source: thyroid carcinoma

Morphology: adherent, large spindle-shaped cells growing as monolayer

Culture Properties: monolayer

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Cat.No.

CSC-C0290

Description

Established from the primary tumor of a 67-year-old woman with primary thyroid carcinoma (undifferentiated carcinoma, composed of spindle, polygonal and giant cells)

Species

Human

Source

thyroid carcinoma

Recommended Medium

80-90% RPMI-1640 + 10-20% h.i. FBS

Culture Properties

monolayer

Morphology

adherent, large spindle-shaped cells growing as monolayer

Karyotype

Human flat-moded hypertriploid karyotype with 22% polyploidy - 74(67-76)<3n>XXX, -2, +9, -10, -12, -13, +14, +15, +15, +18, -19, +20, +4mar, 1-20 dm in most cells, der(6)t(6;7)(q22;q36q11.23), add(15)(p11)x2, del(17)(p12)x2 - subclonal rearrangements, e.g

Quality Control

Mycoplasma: negative in DAPI, microbiological culture, RNA hybridization assays
Immunology: cytokeratin +, cytokeratin-7 +, cytokeratin-8 +, cytokeratin-17 -, cytokeratin-18 +, cytokeratin-19 -, desmin -, endothel -, EpCAM -, GFAP +, neurofilament -, thyr

Storage and Shipping

Frozen with 70% medium, 20% FBS, 10% DMSO at about 1 x 10^6 cells/ampoule; ship in dry ice; store in liquid nitrogen

Citation Guidance

If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.

Are there specific markers or antigens used to identify thyroid tumor cells?

Yes, some specific markers and antigens can be used to identify thyroid tumor cells. For example, thyroid-specific markers such as thyroglobulin and thyroid transcription factor-1 (TTF-1) can be detected using immunohistochemistry or flow cytometry to confirm the thyroid origin of the tumor cells.

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Average Rating: 5.0 | 1 Scientist has reviewed this product

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This cell product has been instrumental in advancing my research. I trust this supplier for my research needs.

24 Apr 2023

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For research use only. Not for any other purpose.