FTC-133

Cat.No.: CSC-6254W

Species: Homo sapiens, human

Source: Thyroid (lymph node metastasis)

Morphology: Polymorphic

Culture Properties: adherent

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Cat.No.

CSC-6254W

Description

FTC-133 was isolated from a lymph node metastasis of a follicular thyroid carcinoma. The morphology differs from flat polygonal to spindle formed cells. They retained differentiated thyrocyte function and thyrocyte responsiveness to thyrotropin and local active growth factors. Thyroglobulin immunoreactivity could be shown in the cytoplasm and EGF receptor immunoreactivity could be visualised on the cell membranes. Complex chromosomal changes were detected as well as a p53 mutation.

Species

Homo sapiens, human

Source

Thyroid (lymph node metastasis)

Recommended Medium

DMEM/Ham's F12 + 10% h.i. FBS.

Culture Properties

adherent

Morphology

Polymorphic

STR DNA Profile

Amelogenin: X
CSF1PO: 10
D13S317: 11
D16S539: 11
D5S818: 12
D7S820: 9,10
THO1: 9.3
TPOX: 9
vWA: 15,18

Karyotype

Complex chromosomal changes

Applications

Function of human thyroid and development of thyroid cancer.

Disease

Thyroid gland follicular carcinoma

Quality Control

Tests for mycoplasma, bacteria and fungi were negative

Storage and Shipping

liquid nitrogen vapor phase

Citation Guidance

If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.

Can thyroid tumor cell cultures be used to study the effects of radiation or other treatments?

Yes, thyroid tumor cell cultures can be used to study the effects of radiation therapy and other treatments. By exposing the cells to specific doses of radiation or other therapeutic agents, researchers can assess their impact on cell survival, DNA damage, and other relevant endpoints.

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Average Rating: 5.0 | 1 Scientist has reviewed this product

Commendable

The company's commitment to scientific research is commendable, and its tumor cells have been an invaluable resource in my studies.

02 Nov 2023

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For research use only. Not for any other purpose.