SK-N-DZ

Cat.No.: CSC-C9368J

Species: Homo sapiens (human)

Specification
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Cat.No.

CSC-C9368J

Description

Spontaneously transformed cells from a female patient with neuroblastoma. The tumour was derived from a bone marrow metastasis and is tumourigenic in nude mice. Used in the study of MIBG uptake in the diagnosis and treatment of neuroblastoma. MIBG is a derivative of the antihypertensive agent guanethidine and is used as a radiopharmaceutical. SK-N-DZ is characterised by low saturable kinetics and predominant linear pattern of uptake of MIBG, with a poor ability to maintain high intracellular levels of the drug.

Species

Homo sapiens (human)

Tissue of Origin

Brain

Recommended Medium

DMEM or EMEM (EBSS) + 2mM Glutamine + 1% Non Essential Amino Acids (NEAA) + 10% Fetal Bovine Serum (FBS)

Storage

Liquid Nitrogen (-180 °C).

Storage and Shipping

Creative Bioarray ships frozen cells on dry ice. On receipt, immediately transfer frozen cells to liquid nitrogen (-180 °C) until ready for experimental use. Never can cryopreserved cells be kept at -20 °C.

Citation Guidance

If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.

What happens to the cells after bacterial contamination during the cell culture process?

When observed at high magnification with an ordinary inverted microscope, a large number of granules are visible in the cytoplasm; the cells grow slowly and gradually become round and fall off.

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Average Rating: 5.0 | 1 Scientist has reviewed this product

Good growth

Cells grow well without any abnormalities in the medium.

25 July 2021

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IMR-5

Description: Species: human, Caucasian;
Tumor: neuroblastoma

Cat#: CSC-6268W INQUIRY

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SK-N-F1

Description: Species: human male;
Tumor: neuroblastoma;
Derived from: bone marrow metastasis

Cat#: CSC-6314W INQUIRY

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U87/DK

Description: Species: human;
Tissue: brain;
Tumor: glioblastoma;
Transfected with binase (ATP binding site 721), mutated de 2-7 EGFR

Cat#: CSC-6323W INQUIRY

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U87/WT

Description: Species: human;
Tissue: brain;
Tumor: glioblastoma;
Transfected with: Transfected with wt EGFR

Cat#: CSC-6324W INQUIRY

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MHH-NB-11

Description: Established from a neuroblastoma metastasis at an adrenal site of a 4-year-old white boy in 1986; cells were described to express neuron-specific enolase and synaptophysin (but neither GFAP nor S-100 protein) and to carry a 20-fold amplification of MYCN (NMYC, N-myc)

Cat#: CSC-C0304 INQUIRY

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GAMG

Description: Established from the biopsy specimens from a 42-year-old woman with glioma (histologically defined as glioblastoma)

Cat#: CSC-C0345 INQUIRY

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For research use only. Not for any other purpose.