Immortalized Human Gastric Cells (KMU-CS12)

Cat.No.: CSC-I9337L

Species: Homo sapiens

Source: Stomach

Morphology: Polygonal

Culture Properties: Adherent

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Cat.No.

CSC-I9337L

Description

The Immortalized Human Gastric Cells (KMU-CS12) were derived from isolated gastric cell clones developed from gastric biopsy samples and were spontaneously immortalized in subsequent cultures. The growth of this cell line was found to be significantly faster than its parental gastric cells. This cell line shows cancer cell phenotypes with tumorigenic ability as tested in immunodeficient nude mice. Another unique characteristic of the Immortalized Human Gastric Cells (KMU-CS12) is the high expression of homeobox genes: HOXA4, HOXA5, HOXA7, HOXA9, and HOXA13. This makes the cell line useful in the construction of HOXA genes knockdown models as well as in research focusing on the chromosomal mutations in HOXA gene family. The Immortalized Human Gastric Cells (KMU-CS12) is also valuable in cancer research particularly in the etiology and studying new therapeutic strategy for gastric cancer.

Species

Homo sapiens

Source

Stomach

Culture Properties

Adherent

Morphology

Polygonal

Immortalization Method

Spontaneous immortalization in subsequent culture with activated hTERT

Markers

Oct-4, Musashi-1, TFF-1, CK8, CK18, EMA

Applications

For Research Use Only

Storage

Directly and immediately transfer cells from dry ice to liquid nitrogen upon receiving and keep the cells in liquid nitrogen until cell culture needed for experiments.

Note: Never can cells be kept at -20 °C.

Shipping

Dry Ice.

Recommended Products

CIK-HT013 HT® Lenti-hTERT Immortalization Kit
CIK-HT003 HT® Lenti-SV40T Immortalization Kit

Quality Control

1) Immunocytochemical staining to assess gene expression;
2) Cell proliferation and differentiation assay;
3) Spectral karyotype analysis (SKY)

BioSafety Level

Citation Guidance

If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.

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