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Genetic factors can play a role, especially in certain inherited syndromes such as Lynch syndrome and hereditary nonpolyposis colorectal cancer (HNPCC).
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Average Rating: 5.0 | 1 Scientist has reviewed this product
Highly recommended
The compatibility of this cell product with various test techniques allowed for seamless integration into my experimental workflows, simplifying data generation and analysis.
09 Jan 2023
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Description: The HeLa 382 cell line is a subclone of the cell line HeLa. The original HeLa cell line was derived from a cervical carcinoma from a 31 year old female and the HeLa 382 cell line was transfected with pBact, expression vector under control of the human beta actin promotor, resistant to G418S. Control to HeLa 422 and HeLa 432.
Description: The HeLa 422 cell line is a subclone of the cell line HeLa. The original HeLa cell line was derived from a cervical carcinoma from a 31 year old female and the HeLa 422 cell line was transfected with ER-pBact, human estrogen receptor cDNA, under control of the human beta actin promotor, resistant to G418S.;
Description: Transfected with the exon 4 defective variant of ER-pBact cDNA, human estrogen receptor cDNA, under control of the human beta actin promotor, resistant to G418S.
Species: human, Black female 31 years old
Tissue: cervix
Tumor: carcinoma, epitheloid
Original line: HeLa
Description: These cells were cloned from the GIRARDI HEART cell line (passage #623) in 1981 and were thought to "represent human heart cells"; however, isoenzyme analysis (Nelson-Rees et al., Science 191: 96-97, 1976) and DNA fingerprinting at the Creative Bioarray established unequivocally that this cell line must be considered de facto a subclone of HELA; cells were described to be sensitive to various toxins and hormones
Description: These cells were cloned from the GIRARDI HEART cell line (passage #623) in 1981 and were thought to "represent human heart cells"; however, isoenzyme analysis (Nelson-Rees et al., Science 191: 96-97, 1976) and DNA fingerprinting at the Creative Bioarray established unequivocally that this cell line must be considered de facto a subclone of HELA; cells were described to be sensitive to various toxins and hormones
