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HOTHC
Cat.No.: CSC-C6471J
Species: Human
Morphology: epithelial-like
Culture Properties: Adherent cells
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Store in liquid nitrogen.
Tumor cells can develop drug resistance through various mechanisms, including genetic mutations, activation of drug efflux pumps, altered drug metabolism, and activation of survival pathways. Drug resistance poses a significant challenge in cancer treatment, necessitating the development of alternative therapeutic strategies.
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Average Rating: 5.0 | 1 Scientist has reviewed this product
Reliable performance
I've tried other cell products, but this one stands out in terms of reliability and performance.
13 Aug 2023
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Description: FTC-133 was isolated from a lymph node metastasis of a follicular thyroid carcinoma. The morphology differs from flat polygonal to spindle formed cells. They retained differentiated thyrocyte function and thyrocyte responsiveness to thyrotropin and local active growth factors. Thyroglobulin immunoreactivity could be shown in the cytoplasm and EGF receptor immunoreactivity could be visualised on the cell membranes. Complex chromosomal changes were detected as well as a p53 mutation.
Description: Species: human male 42 years old;
Tissue: thyroid;
Tumor: carcinoma, follicular;
Derived from: lung metastasis
Description: Established from the primary tumor of a 67-year-old woman with primary thyroid carcinoma (undifferentiated carcinoma, composed of spindle, polygonal and giant cells)
Description: Established from the sarcoma of the thyroid gland from a 47-year-old woman in 1985
Description: Established from the tumor tissue of a 76-year-old woman with metastasizing papillary thyroid carcinoma in 1992
