CD34+ Cells

CD34, a transmembrane glycoprotein expressed on the surface of hematopoietic progenitor cells and small vascular endothelial cells, is considered to be a marker of hematopoietic stem cells and hematopoietic progenitor cells. CD34+ cells have been shown to possess colony-forming potential in short-term assays, maintain long-term colony-forming potential in in vitro culture, and allow the expression and differentiation of blood cells from different hematopoietic lineages in in vivo models. The CD34+ progenitor cells contain two main cell subpopulations, hematopoietic and endothelial progenitor cells. Therefore, CD34+ progenitor cells are suitable for a range of studies, such as directed differentiation into more committed types of blood cells and endothelial lineages.