ActoFactor™ Human Interleukin 2

Specification

Cat.No.

CSC-CTK0004G

Description

IL-2 is a cytokine signaling molecule that is mainly produced by T cells. It is a central regulator of immune responses and plays a role in anti-inflammatory reactions, hematopoiesis and tumor surveillance.

Source

E coli.

Sequence

APTSSSTKKT QLQLEHLLLD LQMILNGINN YKNPKLTRML TFKFYMPKKA TELKHLQCLE EELKPLEEVL NLAQSKNFHL RPRDLISNIN VIVLELKGSE TTFMCEYADE TATIVEFLNR WITFCQSIIS TLT

Molecular Mass

Approximately 15.4 kDa, a single non-glycosylated polypeptide chain containing 133 amino acids

Size

5μg, 100μg, 500μg, 1000μg

Purity

> 98 %

Activity

Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine CTLL-2 cells is less than 0.1 ng/ml, corresponding to a specific activity of > 1.0 × 107 IU/mg

Endotoxin Level

<0.01EU/μg

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled H2O to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions. Do not reconstitute in cell culture media directly.

Usage

This GMP product can be for research use or further manufacturing use.(NOT FOR HUMAN USE)

Storage

Store lyophilized cytokine at -20°C to -80°C.
Avoid repeated freeze/thaw cycles.

Shipping

Dry ice

Citation Guidance

If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.

For research use only. Not for any other purpose.

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