ActoFactor™ Human Interleukin 15

Specification

Cat.No.

CSC-CTK0054G

Description

IL-15 is a cytokine with structural similarity to Interleukin-2 (IL-2). Like IL-2, IL-15 binds to and signals through a complex composed of IL-2/IL-15 receptor beta chain (CD122) and the common gamma chain (gamma-C, CD132). IL-15 is secreted by mononuclear phagocytes (and some other cells) following infection by virus(es).

Source

E coli.

Sequence

NWVNVISDLK KIEDLIQSMH IDATLYTESD VHPSCKVTAM KCFLLELQVI SLESGDASIH DTVENLIILA NNSLSSNGNV TESGCKECEE LEEKNIKEFL QSFVHIVQMF INTS

Molecular Mass

Approximately 12.9 kDa, a single non-glycosylated polypeptide chain containing 114 amino acids

Size

5μg, 100μg, 500μg, 1000μg

Purity

> 98 %

Activity

Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine CTLL-2 cells is less than 0.5 ng/ml, corresponding to a specific activity of > 2.0 × 106 IU/mg

Endotoxin Level

<0.01EU/μg

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.

Usage

This GMP product can be for research use or further manufacturing use.(NOT FOR HUMAN USE)

Storage

Store lyophilized cytokine at -20°C to -80°C.
Avoid repeated freeze/thaw cycles.

Shipping

Dry ice

Citation Guidance

If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.

For research use only. Not for any other purpose.

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