ONCO-DG-1

Cat.No.: CSC-C0517

Species: Human

Source: ovary adenocarcinoma

Morphology: epithelial-like adherent cells with large vacuoles growing as monolayers

Culture Properties: monolayer

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Cat.No.

CSC-C0517

Description

Established from the malignant tumor of a 49-year-old woman with well-differentiated oxyphilic papillary thyroid carcinoma (PT2, G1, No, Mo); cells were described to be tumorigenic in nude mice; however, DNA fingerprinting analysis at the Creative Bioarray showed cross-contamination with cell line OVCAR-3; OVCAR-3 line was established from the malignant ascites of a patient with progressive adenocarcinoma of the ovary

Species

Human

Source

ovary adenocarcinoma

Recommended Medium

90% RPMI-1640 + 10% h.i. FBS

Culture Properties

monolayer

Morphology

epithelial-like adherent cells with large vacuoles growing as monolayers

Karyotype

Human hypotriploid karyotype with 8% polyploidy - 59(56-61)<3n>XX, -X, +1, -2, -4, -6, -8, -9, -13, -13, -14, -15, -15, -17, -17, -18, -19, -21, -22, +7-9mar, +0-3 dm, add(1)(p3?5), add(1)(p2?1), add(1)(q11), der(3;15)(p10;q10), add(3)(p14), del(5)(q23),

Quality Control

Mycoplasma: contamination was eliminated with ciprofloxacin (Ciprobay), then negative in microbiological culture, PCR assays
Immunology: cytokeratin +, cytokeratin-7 +, cytokeratin-8 +, cytokeratin-17 +, cytokeratin-18 +, cytokeratin-19 +, desmin -, endot

Storage and Shipping

Frozen with 70% medium, 20% FBS, 10% DMSO at about 2 x 10^6 cells/ampoule; ship in dry ice; store in liquid nitrogen

Citation Guidance

If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.

How can thyroid tumor cell lines be used to study the metastatic potential of thyroid cancer?

Thyroid tumor cell lines can be used to investigate the metastatic potential of thyroid cancer by assessing their invasive properties in vitro and their ability to form tumors in animal models. These studies help understand the molecular mechanisms underlying thyroid cancer metastasis and identify potential therapeutic targets.

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Average Rating: 4.0 | 1 Scientist has reviewed this product

Exceptional quality

The cells performed as expected, and the customer support provided by the company was outstanding.

13 Feb 2023

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For research use only. Not for any other purpose.