ML-1

Cat.No.: CSC-C0493

Species: Homo sapiens, human

Source: Blood

Morphology: Lymphoblastoid

Culture Properties: Suspension

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Cat.No.

CSC-C0493

Description

ML-1 is one of three celll lines isolated in 1978 from the peripheral blood of a 24 year old male patient with acute myeloblastic leukaemia. The cells can convert to more mature cells by the use of DMSO. The Y chromosome could not be detected in this cell line by short tandem repeat (STR)-PCR analysis. It is a known phenomenon that due to the increased genetic instability of cancer cell lines the Y chromosome can be rearranged or lost resulting in lack of detection. The cell line is identical to the source provided by the depositor based on the STR-PCR analysis.

Species

Homo sapiens, human

Source

Blood

Recommended Medium

RPMI-1640 + 10% h.i. FBS.

Culture Properties

Suspension

Morphology

Lymphoblastoid

STR DNA Profile

Amelogenin: X
CSF1PO: 10,11
D13S317: 9,12
D16S539: 9,12
D5S818: 12
D7S820: 9,11
THO1: 7,9.3
TPOX: 8,10
vWA: 16

Karyotype

Not specified

Applications

This cell line is used for tumourigenicity and biochemical studies.

Disease

Adult acute myeloid leukemia

Quality Control

Tests for mycoplasma, bacteria and fungi were negative

Storage and Shipping

liquid nitrogen vapor phase

Citation Guidance

If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.

Can thyroid tumor cell cultures be used for studying tumor heterogeneity?

Yes, thyroid tumor cell cultures can provide insights into tumor heterogeneity. By establishing multiple cell lines derived from different regions or stages of a tumor, researchers can investigate the molecular and phenotypic heterogeneity within the tumor and understand how it may influence tumor behavior and response to therapy.

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Average Rating: 5.0 | 1 Scientist has reviewed this product

A valuable tool

I've been using this cell product for drug discovery, and it has been a valuable tool. The cells were of high quality and reproducible, allowing me to obtain reliable results.

10 Aug 2023

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For research use only. Not for any other purpose.