CAL-62

Cat.No.: CSC-C0480

Species: Human

Source: thyroid anaplastic carcinoma

Morphology: epithelial-like cells growing in monolayers

Culture Properties: monolayer

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Cat.No.

CSC-C0480

Description

Established from the thyroid gland (right lobe) of a 70-year-old woman with thyroid anaplastic carcinoma in 1988; described as being tumorigenic in heterotransplanted nude mice

Species

Human

Source

thyroid anaplastic carcinoma

Recommended Medium

90-95%DMEM + 5-10% h.i.FBS

Culture Properties

monolayer

Morphology

epithelial-like cells growing in monolayers

Karyotype

Human, flat-moded hypertriploid karyotype with 8% polyploidy - 60-76<3n>XX, -X, +3, +3, -4, +6, +7, +9, -11, -14, -18, +19, +20, +20, +2-6mar - del(1)(p34), der(1)t(1;17)(p34;q21), der(3)add(3)(p11)?dup(3)(q21q22)x2-4, del(6)(q15)x2, i(8q), der(?12)t(1;12

Quality Control

Mycoplasma: negative in DAPI, microbiological culture, RNA hybridization, PCR assays
Immunology: cytokeratin +, cytokeratin-7 +, cytokeratin-8 +, cytokeratin-17 -, cytokeratin-18 +, cytokeratin-19 +, desmin +, endothel -, EpCAM +, GFAP -, neurofilament +,

Storage and Shipping

Frozen with 70% medium, 20% FBS, 10% DMSO at about 5 x 10^6 cells/ampoule; ship in dry ice; store in liquid nitrogen

Citation Guidance

If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.

Can thyroid tumor cell cultures be used to investigate the role of tumor microenvironment?

Yes, thyroid tumor cell cultures can be used to study the interactions between tumor cells and their microenvironment. Researchers can co-culture tumor cells with other cell types, such as fibroblasts or immune cells, to mimic the tumor microenvironment and investigate the influence of these interactions on tumor growth, invasion, and response to therapy.

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Average Rating: 5.0 | 1 Scientist has reviewed this product

Excellent capabilities

The cells exhibited excellent proliferation and differentiation capabilities, resulting in successful tissue regeneration.

21 Feb 2023

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For research use only. Not for any other purpose.