ActoFactor™ Recombinant Mouse Interferon lambda 2

Specification

Cat.No.

CSC-CTK0676

Description

IFN lambda-1,-2, and -3 (also known as IL-29, IL-28A and IL-28B respectively) are distantly related to the IL-10 family and Interferons. All three IFN-lambdas uses a distinct receptor system composed of an IFN-lambdaR1 subunit (also called CRF2-12) and IL-10R2 subunit (also called CRF2-14). Signaling through this receptor system induces antiviral defense similar but distinct than the type I Interferons. Recombinant murine IFN-lambda2 is a 19.8 kDa protein containing 175 amino acid residues.

Species

Mouse

Product Overview

Mouse Ifnl2 expressed in E.coli

Molecular Mass

19.8 kDa

Size

CAT# CSC-CTK0676-20 (20 μg); CAT# CSC-CTK0676-100 (100 μg)

Expression System

E.coli

Purity

Greater than 95% as determined by SDS-PAGE and HPLC analysis.

Activity

Determined by its ability to activate STAT following receptor-ligand interaction.

Endotoxin Level

Less than 1 EU/μg.

Formulation

Lyophilized (freeze-dried), sterile powder. Lyophilized with no additives.

Reconstitution

Please centrifuge product briefly before opening vial. The lyophilized protein should be reconstituted in sterile, ultra-pure water to a concentration of 0,1 - 1,0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at -20°C for future use.

Storage & Stability

The lyophilized protein, though stable at room temperature for up to 3 weeks, is best stored desiccated at -20°C. Reconstituted rMu IFN-lambda-2 should be used immediately or stored long-term in undiluted working aliquots at -20°C. Avoid repeated freeze-thaw cycles.

Citation Guidance

If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.

For research use only. Not for any other purpose.

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