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ActoFactor™ Recombinant Human Selectin P (granule membrane protein 140kDa, antigen CD62)
- Specification
Cat.No.
CSC-CTK0652
Description
P-selectin also called Platelet Alpha-Granule Membrane Protein, CD62, or Granulocyte Membrane Protein GRMP belongs to a family of divalent cation-dependent carbohydrate- binding glycoproteins or adhesion molecules. P-selectin is expressed transiently on the surface of activated platelets and endothelial cells. P-selectin is a 140 kDa protein which is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Secreted P-selectin is thought to play a key role in the adhesion of platelets to monocytes and neutrophils during an inflammatory response. P-selectin is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Levels of P-selectin may be elevated in a number of pathological conditions.|Human recombinant P-selectin produced in E. coli contains 566 amino acids 197-761 which are fused to an amino-terminal hexa-histidine tag.
Species
Human
Product Overview
Human SELP expressed in E.coli
Molecular Mass
140 kDa
Size
CAT# CSC-CTK0652-10 (10 μg); CAT# CSC-CTK0652-50 (50 μg)
Expression System
E.coli
Purity
Greater than 95% as determined by SDS-PAGE analysis.
Activity
N/A
Endotoxin Level
N/A
Formulation
Sterile-filtered, liquid formulation. P-selectin is supplied in 50% glycerol.
Reconstitution
Please centrifuge product briefly before opening vial. The protein solution can be diluted into other aqueous buffers and stored at -20°C for future use.
Storage & Stability
For long-term storage, protein solution should be stored at -20°C. Avoid repeated freeze / thaw cycles.
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.
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