ActoFactor™ Recombinant Human Prospero homeobox 1

Specification

Cat.No.

CSC-CTK0556

Description

Prox-1 is a homeobox gene and acts as a master switch for lymphatic endothelial phenotype. Expression of Prox-1 in blood endothelial cells induces expression of other lymphatic marker genes. Together with Podoplanin, Prox-1 can be used to reliably distinguish lympathic vessels from blood vessels. Prox1 is expressed in CNS, eye, pancreas, liver and heart, and it is one of the most specific and reliable markers for lymphatic endothelial cells. The highly conserved C- terminal part of the homeobox transcription factor Prox1 was produced in E. coli. It was not tested for activity and can be used as positive control e.g. in Western analysis.

Species

Human

Product Overview

Human PROX1 expressed in E.coli

Molecular Mass

25 kDa

Size

CAT# CSC-CTK0556-5 (5 μg); CAT# CSC-CTK0556-25 (25 μg)

Expression System

E.coli

Purity

Greater than 95% as determined by SDS-PAGE analysis.

Activity

N/A

Endotoxin Level

N/A

Formulation

Sterile-filtered and lyophilized from a protein solution in PBS buffer.

Reconstitution

Please centrifuge product briefly before opening vial. The lyophilized protein should be reconstituted in sterile, ultra-pure water to a concentration of 0,1 - 1,0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at -20°C for future use.

Storage & Stability

The lyophilized protein is best stored desiccated at -20°C. It should be used immediately or stored long-term in undiluted working aliquots at -20°C. Avoid repeated freeze-thaw cycles.

Citation Guidance

If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.

For research use only. Not for any other purpose.

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