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ActoFactor™ Recombinant Human Myotrophin
- Specification
Cat.No.
CSC-CTK0469
Description
MTPN is an ankyrin repeat protein, that stimulates protein synthesis and cardiomyocyte growth to commence cardiac hypertrophy by activating the NF-kappaB signaling cascade. Myotrophin participates in cerebellar morphogenesis and takes part in differentiation of cerebellar neurons, particularly of granule cells. High levels of MTPN are expressed in human dilated cardiomyopathic and ischemic hearts. Recombinant human MTPN produced in E. coli is a single, non-glycosylated polypeptide chain of 138 amino acids (1-118 a.a.) and a molecular mass of 15 kDa. The MTPN is fused to a 20 amino acid His-Tag at the N-terminus and purified by proprietary chromatographic techniques.
Species
Human
Product Overview
Human MTPN expressed in E.coli
Molecular Mass
15 kDa
Size
CAT# CSC-CTK0469-20 (20 μg); CAT# CSC-CTK0469-100 (100 μg)
Expression System
E.coli
Purity
Greater than 90% as determined by SDS-PAGE analysis.
Activity
N/A
Endotoxin Level
Less than 1 EU/μg.
Formulation
Protein solution containing 20 mM Tris-HCl (pH 8.0) and 10% glycerol.
Reconstitution
Please centrifuge product briefly before opening vial. The dissolved protein can be diluted into other aqueous buffers and stored at -20°C for future use.
Storage & Stability
Store at 4°C if entire vial will be used within 1 week. Store frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles.
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.
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