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ActoFactor™ Recombinant Human C-reactive protein, pentraxin-related
- Specification
Cat.No.
CSC-CTK0481
Description
CRP is an acute phase protein that correlates with inflammatory diseases and is synthesized by hepatocytes during the acute phase response by certain cytokines (IL-1 and TNF-alpha and - beta). CRP levels increase dramatically (up to 1,000 fold) and serve as a useful marker of inflammation in such conditions as bacterial infection, rheumatoid arthritis, viral infections, transplantation rejection, meningitis, myocardial infarction, septicemia, osteomyelitis and others. CRP is also highly correlated to Serum Amyloid A levels. |Recombinant Human CRP produced in E. coli is a non-glycosylated polypeptide chain having a total molecular mass of 115 kDa corresponding to a pentamer structure of 23 kDa monomers determined by amino acid sequence. The CRP has been purified by using proprietary chromatographic techniques.
Species
Human
Product Overview
Human CRP expressed in E.coli
Molecular Mass
115 kDa
Size
CAT# CSC-CTK0481-500 (500 μg); CAT# CSC-CTK0481-2500 (2.5 mg)
Expression System
E.coli
Purity
Greater than 95% as determined by SDS-PAGE and RP-HPLC analysis.
Activity
N/A
Endotoxin Level
N/A
Formulation
Sterile-filtered, clear solution in 20 mM Tris (pH 7.5), 2 mM CaCl2, 0.14 M NaCl and 0.05% NaN3.
Reconstitution
Please centrifuge product briefly before opening the vial. The protein solution can be diluted into other aqueous buffers and stored at 40C for future use.
Storage & Stability
The lyophilized powder, though stable at room temperature for up to 3 weeks, is best stored desiccated at -20°C. Reconstituted protein should be stored long-term in undiluted working aliquots at –20°C. For long-term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze / thaw cycles.
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.
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