8505C

Cat.No.: CSC-C2224

Species: Human

Source: thyroid carcinoma

Morphology: epithelial-like adherent cells growing as monolayer

Culture Properties: monolayer

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Cat.No.

CSC-C2224

Description

Established from the primary tumor of a 78-year-old woman with thyroid carcinoma (undifferentiated carcinoma, histologically a largely papillary adenocarcinoma with some spindle, polygonal and giant cells)

Species

Human

Source

thyroid carcinoma

Recommended Medium

90% RPMI-1640 + 10% h.i. FBS

Culture Properties

monolayer

Morphology

epithelial-like adherent cells growing as monolayer

Karyotype

Human hypotriploid karyotype with 16% polyploidy - 65(57-68)<3n>XX, -X, -2, +3, -7, -10, +11, -13, -16, -18, -19, +2mar, del(1)(q13), del(3)(q22), ?del(4)(q21), i(8q)

Quality Control

Mycoplasma: negative in DAPI, microbiological culture, RNA hybridization assays
Immunology: cytokeratin +, cytokeratin-7 +, cytokeratin-8 +, cytokeratin-17 -, cytokeratin-18 +, cytokeratin-19 +, desmin -, endothel -, EpCAM +, GFAP -, HMB-45 -, neurofilame

Storage and Shipping

Frozen with 70% medium, 20% FBS, 10% DMSO at about 1 x 10^6 cells/ampoule; ship in dry ice; store in liquid nitrogen

Citation Guidance

If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.

Can thyroid tumor cell cultures be used for high-throughput screening of potential anti-cancer compounds?

Yes, thyroid tumor cell cultures can be used for high-throughput screening of potential anti-cancer compounds. Large libraries of chemical compounds can be tested on thyroid tumor cells to identify molecules with anti-cancer activity, providing a basis for further development of novel therapies.

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Average Rating: 4.0 | 1 Scientist has reviewed this product

Well characterized

This cell product has been a game-changer for my experiments. The cells were well-characterized, and the provided protocols were clear and easy to follow. I'm extremely satisfied with my purchase.

10 May 2023

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For research use only. Not for any other purpose.