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VEGFR2 FISH Probe
- Specification
Cat.No.
FONC-133
Description
Creative Bioarray is proud to present our Custom VEGFR2 FISH Probe, specifically designed to detect and confirm rearrangements of the VEGFR2 gene.
The VEGFR2 (Vascular Endothelial Growth Factor Receptor 2) gene plays a critical role in angiogenesis, the process of new blood vessel formation. It is primarily expressed in endothelial cells and is a key mediator of the effects of vascular endothelial growth factor (VEGF). Abnormalities in VEGFR2, including gene rearrangements, can lead to dysregulated angiogenesis, contributing to various pathological conditions, including cancer, where tumor growth and metastasis are often driven by enhanced blood supply.
Clinical Relevance: Detecting rearrangements of the VEGFR2 gene is essential for understanding the molecular mechanisms underlying tumor angiogenesis and progression. Identifying these genetic alterations can provide valuable insights into disease prognosis and may inform targeted therapeutic strategies, particularly in cancers where VEGFR2 plays a pivotal role. The VEGFR2 pathway is a well-established target for anti-angiogenic therapies, making the detection of its rearrangements crucial for personalized treatment approaches.
Our Custom VEGFR2 FISH Probe is an invaluable tool for researchers dedicated to exploring the role of VEGFR2 in cancer biology and advancing targeted therapies aimed at inhibiting angiogenesis.
The VEGFR2 (Vascular Endothelial Growth Factor Receptor 2) gene plays a critical role in angiogenesis, the process of new blood vessel formation. It is primarily expressed in endothelial cells and is a key mediator of the effects of vascular endothelial growth factor (VEGF). Abnormalities in VEGFR2, including gene rearrangements, can lead to dysregulated angiogenesis, contributing to various pathological conditions, including cancer, where tumor growth and metastasis are often driven by enhanced blood supply.
Clinical Relevance: Detecting rearrangements of the VEGFR2 gene is essential for understanding the molecular mechanisms underlying tumor angiogenesis and progression. Identifying these genetic alterations can provide valuable insights into disease prognosis and may inform targeted therapeutic strategies, particularly in cancers where VEGFR2 plays a pivotal role. The VEGFR2 pathway is a well-established target for anti-angiogenic therapies, making the detection of its rearrangements crucial for personalized treatment approaches.
Our Custom VEGFR2 FISH Probe is an invaluable tool for researchers dedicated to exploring the role of VEGFR2 in cancer biology and advancing targeted therapies aimed at inhibiting angiogenesis.
Size
10 Tests; 20 Tests
Label
Orange/Green/Aqua
Locus
4q12
Specificity
Human
Usage
For Research Use Only. Not for use in diagnostic procedures.
Storage
Store at minus 20 centigrade in the dark
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.
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