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TRAF3 FISH Probe
- Specification
Cat.No.
FONC-148
Description
TRAF3 FISH Probe is expertly designed to detect amplifications and deletions of the TRAF3 gene. This vital probe is labeled in vibrant orange for optimal visualization, and we offer customization options to meet your specific research requirements.
The TRAF3 (TNF Receptor Associated Factor 3) gene plays a crucial role in the immune response and is involved in signaling pathways that regulate the activation of NF-kB and other transcription factors. Aberrations in TRAF3 have been associated with various malignancies, particularly lymphoid cancers such as multiple myeloma and lymphomas. These alterations may disrupt normal signaling pathways, contributing to tumorigenesis.
Clinical Relevance: Detecting TRAF3 amplifications and deletions is essential for understanding the genetic basis of associated hematological malignancies. The presence of TRAF3 alterations may influence disease prognosis and treatment decisions. In particular, TRAF3 deletions have been linked to poor clinical outcomes, highlighting the importance of monitoring its genomic status in patients.
Utilizing our TRAF3 FISH Probe allows researchers to enhance their understanding of the genetic landscape associated with TRAF3 dysregulation. This probe is an invaluable tool for advancing research in oncology and hematology, facilitating the identification of genetic changes that may impact patient management.
The TRAF3 (TNF Receptor Associated Factor 3) gene plays a crucial role in the immune response and is involved in signaling pathways that regulate the activation of NF-kB and other transcription factors. Aberrations in TRAF3 have been associated with various malignancies, particularly lymphoid cancers such as multiple myeloma and lymphomas. These alterations may disrupt normal signaling pathways, contributing to tumorigenesis.
Clinical Relevance: Detecting TRAF3 amplifications and deletions is essential for understanding the genetic basis of associated hematological malignancies. The presence of TRAF3 alterations may influence disease prognosis and treatment decisions. In particular, TRAF3 deletions have been linked to poor clinical outcomes, highlighting the importance of monitoring its genomic status in patients.
Utilizing our TRAF3 FISH Probe allows researchers to enhance their understanding of the genetic landscape associated with TRAF3 dysregulation. This probe is an invaluable tool for advancing research in oncology and hematology, facilitating the identification of genetic changes that may impact patient management.
Size
10 Tests; 20 Tests
Label
Orange/Green
Locus
14q32.32
Specificity
Human
Usage
For Research Use Only. Not for use in diagnostic procedures.
Storage
Store at minus 20 centigrade in the dark
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.
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