SuperQuick® Rat Phase I Metabolic Stability Kit (Female)

DMK-M007

Liver microsomes contain the majority of phase I enzymes, of which the most important is CYP450 oxidase family. When liver microsome is supplemented with enzyme cofactor of NADPH, phase I metabolic system can be reconstructed and used to study the phase I metabolic stability of drug candidates by In Vitro incubation.

In Vitro Assessment of Metabolic Stability

Microsome
Substrate
NADPH regeneration system
0.1 M PBS(pH7.4)

0.2 mL*50 test

Store at -70°C.

Dry ice

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