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PTPRT/MYBL2 FISH Probe
- Specification
Cat.No.
FONC-123
Description
PTPRT/MYBL2 FISH Probe is expertly designed to detect deletions in the chromosome 20q region encompassing the PTPRT and MYBL2 genes. This probe is available with vibrant green and orange labeling for clear visualization, and customization options are offered to meet your specific research requirements.
PTPRT (Protein Tyrosine Phosphatase Receptor Type T) and MYBL2 (MYB Like 2) are both critical genes located in the 20q region, playing significant roles in cellular signaling and regulation of cell cycle progression. Deletions in this region have been associated with various hematological malignancies, including acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS).
Clinical Relevance: The detection of deletions involving PTPRT and MYBL2 is essential for understanding the genetic landscape of these diseases. Loss of PTPRT function can disrupt normal signaling pathways, contributing to tumorigenesis, while alterations in MYBL2 are linked to cell proliferation and differentiation. Identifying these deletions can provide valuable insights into disease prognosis and may guide therapeutic decisions.
Our PTPRT/MYBL2 FISH Probe is a vital tool for researchers focused on unraveling the complexities of cancer genetics and improving patient management strategies.
PTPRT (Protein Tyrosine Phosphatase Receptor Type T) and MYBL2 (MYB Like 2) are both critical genes located in the 20q region, playing significant roles in cellular signaling and regulation of cell cycle progression. Deletions in this region have been associated with various hematological malignancies, including acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS).
Clinical Relevance: The detection of deletions involving PTPRT and MYBL2 is essential for understanding the genetic landscape of these diseases. Loss of PTPRT function can disrupt normal signaling pathways, contributing to tumorigenesis, while alterations in MYBL2 are linked to cell proliferation and differentiation. Identifying these deletions can provide valuable insights into disease prognosis and may guide therapeutic decisions.
Our PTPRT/MYBL2 FISH Probe is a vital tool for researchers focused on unraveling the complexities of cancer genetics and improving patient management strategies.
Size
10 Tests; 20 Tests
Label
Orange/Green
Locus
20q12/20q13.12
Specificity
Human
Usage
For Research Use Only. Not for use in diagnostic procedures.
Storage
Store at minus 20 centigrade in the dark
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.
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