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Immortalized Human Adult Hepatocytes (hepaRG)

Cat.No.: CSC-I2321Z

Species: Human

Culture Properties: Adherent

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Cat.No.
CSC-I2321Z
Description
HepaRG cells are a human liver-derived cell line originally established from a hepatocellular carcinoma. They are unique due to their ability to differentiate into hepatocyte-like and biliary-like cells under specific culture conditions. HepaRG cells are widely used in liver-related research, particularly for studying drug metabolism, hepatotoxicity, and liver disease mechanisms.

Key features of HepaRG cells include:
Origin: Human hepatocellular carcinoma.
Differentiation: Can differentiate into hepatocyte-like and biliary-like cells.
Applications: Drug metabolism studies, toxicity testing, and liver disease research.
Relevance: Express key liver enzymes (e.g., CYP450 enzymes) and transporters, making them a valuable model for liver function studies.
HepaRG cells are a reliable in vitro model for mimicking human liver functions in research and drug development.
Species
Human
Recommended Medium
hepaRG Medium
Freezing Medium
Complete medium supplemented with 10% (v/v) DMSO
Culture Properties
Adherent
Immortalization Method
HepaRG cells are not artificially immortalized using genetic modifications like many other cell lines. Instead, their immortalization is naturally derived from the fact that they originate from a hepatocellular carcinoma (HCC).
Shipping
Dry Ice
Quality Control
free from contaminations (bacteria incl. mycoplasma, fungi, HIV, HAV, HBV, HCV, Parvo-B19) and cross-contaminations
Storage and Shipping
Directly and immediately transfer cells from dry ice to liquid nitrogen upon receiving and keep the cells in liquid nitrogen until cell culture needed for experiments.

Note: Never can cells be kept at -20°C.
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.

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