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DUSP22 Break Apart FISH Probe
- Specification
Cat.No.
FONC-135
Description
DUSP22 Break Apart FISH Probe is specifically designed to detect translocations involving the DUSP22 gene. This probe features vibrant orange and green labeling for clear visualization, and we offer customization options to meet your specific research requirements.
The DUSP22 (Dual Specificity Phosphatase 22) gene encodes a protein that plays a crucial role in regulating cellular signaling pathways by dephosphorylating both tyrosine and serine/threonine residues. DUSP22 is involved in various cellular processes, including cell proliferation, differentiation, and apoptosis. Translocations involving DUSP22 have been implicated in certain hematological malignancies, particularly in aggressive forms of lymphoma, such as anaplastic large cell lymphoma (ALCL) and other T-cell lymphomas.
Clinical Relevance: The detection of DUSP22 translocations is essential for the accurate diagnosis and classification of lymphoproliferative disorders. Identifying these genetic alterations can provide valuable insights into disease prognosis and may inform targeted therapeutic strategies. The presence of DUSP22 translocations is associated with specific clinical features and can influence treatment decisions, making it a critical biomarker in the management of patients with lymphomas.
Our DUSP22 Break Apart FISH Probe is an invaluable tool for researchers dedicated to understanding the role of DUSP22 in cancer biology and advancing targeted therapies for patients with translocation-associated malignancies.
The DUSP22 (Dual Specificity Phosphatase 22) gene encodes a protein that plays a crucial role in regulating cellular signaling pathways by dephosphorylating both tyrosine and serine/threonine residues. DUSP22 is involved in various cellular processes, including cell proliferation, differentiation, and apoptosis. Translocations involving DUSP22 have been implicated in certain hematological malignancies, particularly in aggressive forms of lymphoma, such as anaplastic large cell lymphoma (ALCL) and other T-cell lymphomas.
Clinical Relevance: The detection of DUSP22 translocations is essential for the accurate diagnosis and classification of lymphoproliferative disorders. Identifying these genetic alterations can provide valuable insights into disease prognosis and may inform targeted therapeutic strategies. The presence of DUSP22 translocations is associated with specific clinical features and can influence treatment decisions, making it a critical biomarker in the management of patients with lymphomas.
Our DUSP22 Break Apart FISH Probe is an invaluable tool for researchers dedicated to understanding the role of DUSP22 in cancer biology and advancing targeted therapies for patients with translocation-associated malignancies.
Size
10 Tests; 20 Tests
Label
Orange/Green/Aqua
Locus
6p25.3
Specificity
Human
Usage
For Research Use Only. Not for use in diagnostic procedures.
Storage
Store at minus 20 centigrade in the dark
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.
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