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Testosterone Propionate-Induced Androgenetic Alopecia (AGA) Model
Creative Bioarray has developed a state-of-the-art model of Androgenetic Alopecia (AGA) induced by testosterone propionate for our clients. This innovative model accurately mimics the physiological conditions associated with AGA, a common condition affecting millions of individuals worldwide. By utilizing testosterone propionate, we provide a reliable and standardized platform for researchers to investigate the underlying mechanisms of hair loss and to evaluate potential therapeutic interventions.
Our Testosterone Propionate-Induced Androgenetic Alopecia (AGA) Model
Animal Species
Mouse
Modeling Method
Animals are subcutaneously injected with testosterone propionate for four weeks after hair removal.
Endpoints
- Body weight
- Hair growth evaluation (photo of mice)
- Histology analysis: H&E staining
- qPCR or Western blot
- Other customized endpoints according to your specific needs
Example Data
Fig. 1 Analysis of morphological and histological changes caused by Stauntonia hexaphylla extract in the testosterone propionate (TP)-induced androgenic alopecia (AGA) mouse model. A, Comparison of back skin colors and hair growth in TP-induced C57BL/6 mice; B, Hair growth score; C, Comparison of histological images of hair follicles (longitudinal view, A - D (100X) transverse view, E - H (100X), I - L (400X); D, the dermis, S; subcutaneous); D, Dermal thickness; E, Quantification of cross-sectional diameters of the hair shaft/inner root sheath (IRS); F, Follicular numbers were assessed. Values are expressed as mean ± standard deviation. (Hong et al., 2023)
Quotation and Ordering
Creative Bioarray is committed to advancing dermatological research and empowering our clients with the tools they need to make significant strides in understanding and treating AGA. If you are interested in our services, please feel free to contact us at any time or submit an inquiry to us direclt.
Reference
- Hong, G.L., et al. Stauntonia hexaphylla Extract Ameliorates Androgenic Alopecia by Inhibiting Androgen Signaling in Testosterone-induced Alopecia Mice. Iran J Pharm Res. 2023;21(1): e133333.
For research use only. Not for any other purpose.
