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Del 20q/20p FISH Probe
- Specification
Cat.No.
FONC-140
Description
Del 20q/20p FISH Probe is expertly designed to detect deletions and amplifications in the q arm of chromosome 20, complemented by a chromosome 20 centromeric control for accurate reference. This probe is labeled in vibrant green and orange for optimal visualization, and we offer customization options to meet your specific research requirements.
Chromosome 20 is known to harbor several genes that play critical roles in various cellular processes, including cell growth, differentiation, and apoptosis. Alterations in this chromosome, particularly deletions and amplifications in the 20q and 20p regions, have been implicated in a range of hematological malignancies and solid tumors. These genetic changes can contribute to tumorigenesis by disrupting normal cellular functions and promoting oncogenic pathways.
Clinical Relevance: The detection of deletions and amplifications in the q arm of chromosome 20 is essential for the diagnosis and characterization of various cancers, including acute myeloid leukemia (AML) and certain lymphomas. The presence of these genetic alterations can provide valuable insights into disease prognosis and may inform treatment strategies. For instance, specific amplifications may indicate a more aggressive disease course, while deletions could suggest potential therapeutic targets.
Utilizing our Del 20q/20p FISH Probe allows researchers to gain a deeper understanding of the genetic landscape of tumors, facilitating the development of personalized treatment approaches tailored to the unique genetic profile of each patient.
Chromosome 20 is known to harbor several genes that play critical roles in various cellular processes, including cell growth, differentiation, and apoptosis. Alterations in this chromosome, particularly deletions and amplifications in the 20q and 20p regions, have been implicated in a range of hematological malignancies and solid tumors. These genetic changes can contribute to tumorigenesis by disrupting normal cellular functions and promoting oncogenic pathways.
Clinical Relevance: The detection of deletions and amplifications in the q arm of chromosome 20 is essential for the diagnosis and characterization of various cancers, including acute myeloid leukemia (AML) and certain lymphomas. The presence of these genetic alterations can provide valuable insights into disease prognosis and may inform treatment strategies. For instance, specific amplifications may indicate a more aggressive disease course, while deletions could suggest potential therapeutic targets.
Utilizing our Del 20q/20p FISH Probe allows researchers to gain a deeper understanding of the genetic landscape of tumors, facilitating the development of personalized treatment approaches tailored to the unique genetic profile of each patient.
Size
10 Tests; 20 Tests
Label
Orange/Green/Aqua
Locus
20q12/20p11.21
Specificity
Human
Usage
For Research Use Only. Not for use in diagnostic procedures.
Storage
Store at minus 20 centigrade in the dark
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.
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