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CREB1 FISH Probe
- Specification
Cat.No.
FONC-127
Description
CREB1 FISH Probe is specifically designed to detect amplifications and deletions of the CREB1 gene. This probe features vibrant orange labeling for enhanced visualization, and we offer customization options to meet your specific research needs.
CREB1 (cAMP Response Element-Binding Protein 1) is a transcription factor that plays a pivotal role in regulating gene expression in response to various signaling pathways, particularly those involving cyclic AMP (cAMP). CREB1 is crucial for processes such as cell proliferation, differentiation, and survival. Dysregulation of CREB1 has been implicated in several cancers, including breast cancer, lung cancer, and glioblastoma, where it can contribute to tumorigenesis and cancer progression.
Clinical Relevance: The detection of CREB1 amplifications and deletions is essential for understanding the molecular mechanisms underlying these malignancies. Abnormal expression of CREB1 can lead to altered cellular signaling and promote oncogenic pathways. Identifying these genetic alterations can provide valuable insights into disease prognosis and may inform targeted therapeutic strategies.
Our CREB1 FISH Probe is an indispensable tool for researchers focused on elucidating the role of CREB1 in cancer biology and advancing personalized medicine approaches.
CREB1 (cAMP Response Element-Binding Protein 1) is a transcription factor that plays a pivotal role in regulating gene expression in response to various signaling pathways, particularly those involving cyclic AMP (cAMP). CREB1 is crucial for processes such as cell proliferation, differentiation, and survival. Dysregulation of CREB1 has been implicated in several cancers, including breast cancer, lung cancer, and glioblastoma, where it can contribute to tumorigenesis and cancer progression.
Clinical Relevance: The detection of CREB1 amplifications and deletions is essential for understanding the molecular mechanisms underlying these malignancies. Abnormal expression of CREB1 can lead to altered cellular signaling and promote oncogenic pathways. Identifying these genetic alterations can provide valuable insights into disease prognosis and may inform targeted therapeutic strategies.
Our CREB1 FISH Probe is an indispensable tool for researchers focused on elucidating the role of CREB1 in cancer biology and advancing personalized medicine approaches.
Size
10 Tests; 20 Tests
Label
Orange/Green/Aqua
Locus
2q33
Specificity
Human
Usage
For Research Use Only. Not for use in diagnostic procedures.
Storage
Store at minus 20 centigrade in the dark
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.
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