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BRCA1 FISH Probe
- Specification
Cat.No.
FONC-142
Description
BRCA1 FISH Probe is specifically designed to detect copy number variations (CNVs) in the BRCA1 gene. This probe is an essential tool for researchers and clinicians focused on understanding the genetic underpinnings of breast and ovarian cancers.
The BRCA1 (Breast Cancer 1) gene, located on chromosome 17, plays a critical role in maintaining genomic stability and repairing DNA double-strand breaks. Mutations and copy number variations in BRCA1 are strongly associated with an increased risk of hereditary breast and ovarian cancers. Identifying alterations in BRCA1 is crucial for assessing cancer risk, guiding treatment decisions, and informing genetic counseling for patients and their families.
Clinical Relevance: Detecting BRCA1 copy number variations using our FISH probe is vital for the accurate diagnosis and management of patients with suspected hereditary breast and ovarian cancer syndromes. Understanding the status of BRCA1 can provide insights into tumor behavior, potential treatment options, and eligibility for targeted therapies, such as PARP inhibitors, which have shown efficacy in BRCA-mutated tumors.
Our BRCA1 FISH Probe is labeled in vibrant colors for clear visualization and can be customized to meet specific research needs. By utilizing this probe, researchers can enhance their understanding of BRCA1-related pathologies and improve patient outcomes through personalized medicine approaches.
The BRCA1 (Breast Cancer 1) gene, located on chromosome 17, plays a critical role in maintaining genomic stability and repairing DNA double-strand breaks. Mutations and copy number variations in BRCA1 are strongly associated with an increased risk of hereditary breast and ovarian cancers. Identifying alterations in BRCA1 is crucial for assessing cancer risk, guiding treatment decisions, and informing genetic counseling for patients and their families.
Clinical Relevance: Detecting BRCA1 copy number variations using our FISH probe is vital for the accurate diagnosis and management of patients with suspected hereditary breast and ovarian cancer syndromes. Understanding the status of BRCA1 can provide insights into tumor behavior, potential treatment options, and eligibility for targeted therapies, such as PARP inhibitors, which have shown efficacy in BRCA-mutated tumors.
Our BRCA1 FISH Probe is labeled in vibrant colors for clear visualization and can be customized to meet specific research needs. By utilizing this probe, researchers can enhance their understanding of BRCA1-related pathologies and improve patient outcomes through personalized medicine approaches.
Size
10 Tests; 20 Tests
Label
Orange/Green/Aqua
Locus
17q21.31
Specificity
Human
Usage
For Research Use Only. Not for use in diagnostic procedures.
Storage
Store at minus 20 centigrade in the dark
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.
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