BCR-ABL1 Dual Fusion/Translocation FISH Probe

Cat.No.

FON-161

Description

The BCR-ABL1 FISH probe is designed to detect rearrangements involving regions of the human BCR locus, located on chromosome band 22q11.23, and of the human ABL1 gene on 9q34.12. This product contains two differentially labeled Probes, one probe covers the entire BCR gene along with some upstream (5’) and downstream (3’) flanking untranslated genomic sequences. The probe overlaps the known major and minor breakpoints observed in the region. The second probe spans the complete ABL1 gene on 9q34.12, including the common breakpoint region upstream of exon 2, as well as adjacent 5’ and 3’ untranslated genomic sequences. The probe set is optimized to reveal the typical t(9;22)(q34;q11) translocation as well as other translocations between the two genes, in metaphase and interphase blood or bone marrow cells.

Size

10 Tests

Label

Red/Green/Aqua/Orange

Locus

22q11.23
9q34.12

Specificity

Human

Usage

For Research Use Only. Not for use in diagnostic procedures.

Storage

Store at minus 20 centigrade

Citation Guidance

If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.

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