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- Alzheimer's Disease Modeling and Assays
- Alzheimer's Disease In Vivo Model Service
Disease Models
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Inflammation & Autoimmune Disease Models
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- Carrageenan-Induced Paw Edema Model
- Experimental Autoimmune Myasthenia Gravis (EAMG) Model
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Neurological Disease Models
- Alzheimer's Disease Modeling and Assays
- Seizure Models
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Urology Disease Models
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- 5/6 Nephrectomy Model
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- Passive Heymann Nephritis (PHN) Model
- Adenine-Induced Chronic Kidney Disease (CKD) Model
- Kidney Stone Model
- Doxorubicin-Induced Nephropathy Model
- Orthopedic Disease Models
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Alzheimer's Disease In Vivo Model Service
Creative Bioarray provides customers with customized services using model organisms such as mice, rats and other animals. These models mimic pathological and behavioral hallmarks of Alzheimer’s disease which could facilitate pre-clinical research on the screening of drug effects as well as the mechanisms of action for customers .
Figure. 1. Reproducing plaques and NFTs in transgenic mice.
Creative Bioarray can provide animal models of Alzheimer's disease, including but not limited to:
- Aging models
- Natural aging model
- Senescence-accelerated Prone 8 Mouse Model
- D-gal induced model
- Transgenic animal models
- APP transgenic models
- ApoE transgenic models
- BDNF transgenic models
- Tau transgenic models
- Double transgenic models
- Triple transgenic models
- Five transgenic models
- Induced damage models
- Scopolamine induced model
- Streptozocin(STZ) induced model
- Ibotenic acid (IBO) induced model
- Aβ induced model
- Drosophila models
- Caenorhabditis elegans models
- Danio Rerio models
Our capabilities
- Behavioral and cognitive function tests
- Histopathology assays
- Mechanism/ signaling pathway studies
- Biomarkers discovery
With well skills and experience in AD research field, you can rely on Creative Bioarray’s expertise to evaluate your preclinical drug candidates such as nature compounds, small molecules, biologics and RNA therapeutics in acute and chronic efficacy studies. In addition, with years of experience, Creative Bioarray understands how to help design the studies to obtain rapid and clear answers to meet our customers’ need. Our in vivo animal models are capable of providing a rapid screening of the neuroprotective potential agents for the treatment of AD.
Quotation and ordering
If you have any special needs or questions regarding our services, please feel free to contact us. We look forward to cooperating with you in the future.
Reference
- Götz, Jürgen, Ittner L M . Animal models of Alzheimer's disease and frontotemporal dementia[J]. Nat Rev Neurosci, 2008, 9(7):532-544.
For research use only. Not for any other purpose.
